Gene transcription is controlled largely by transcription factors that bind to enhancers, which are regions of the DNA that loop over to genes to activate them. While silencers have been […]
Researchers Identify Looping Silencers as a Promising Target for Cancer Treatment Read More »
Congratulations to CSI Deputy Director and Senior Principal Investigator, Prof. Chng Wee Joo, on being conferred the Yong Loo Lin School of Medicine Graduate Mentor of the Year (GRAMAY) 2021!
The pathways that control the behaviour of diseased cells involve complex interactions between large molecules like proteins. Protein-protein interactions (PPIs) represent a vast repertoire of potential targets for new drugs
Development of novel Camsirubicin analog expands Monopar’s therapeutic pipeline WILMETTE, Ill., June 03, 2021 (GLOBE NEWSWIRE) — Monopar Therapeutics Inc. (Nasdaq: MNPR), a clinical-stage biopharmaceutical company primarily focused on developing
Jiayi Weng 1, Xiaoqiang Xiang 2, Lingwen Ding 3, Andrea Li-Ann Wong 4, Qi Zeng 5, Gautam Sethi 6, Lingzhi Wang 7, Soo Chin Lee 8, Boon Cher Goh 9 Affiliations 1Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore; Department of Medicine, Yong
Daryl Jin Tai Tay 1, Yangyang Song 1, Boya Peng 2, Tan Boon Toh 3, Lissa Hooi 1, Desiree-Faye Kaixin Toh 4, HuiQi Hong 5, Sze Jing Tang 1, Jian Han 1, Wei Liang Gan 1, Tim Hon Man Chan 1, Manchugondanahalli S Krishna 4, Kiran M Patil 4, Manikantha Maraswami 4, Teck Peng Loh 4, Yock Young Dan 6, Lei Zhou 7, Glenn
Liang Xu 1 2, Ye Chen 1, Yulun Huang 3 4 5, Edwin Sandanaraj 6 7, John S Yu 8, Ruby Yu-Tong Lin 9, Pushkar Dakle 9, Xin-Yu Ke 9, Yuk Kien Chong 6, Lynnette Koh 6 10, Anand Mayakonda 9, Kassoum Nacro 11, Jeffrey Hill 12, Mo-Li Huang 9 13, Sigal Gery 14, See Wee Lim 6, Zhengyun Huang 15, Ying Xu 15, Jianxiang Chen 16 17 18, Longchuan Bai 19 20, Shaomeng Wang 19 20 21 22, Hiroaki Wakimoto 23, Tseng Tsai Yeo 24, Beng Ti
Topography of Transcriptionally Active Chromatin in Glioblastoma (Sci Adv, Apr 2021) Read More »
Inherited faults (‘mutations’) in the breast cancer gene, BRCA2, can lead to cancers of the breast, ovary or other organs. BRCA2 codes for a protein containing 3,418 building blocks (called
Reversing Cancer-Causing Faults in the Breast Cancer Gene BRCA2. Read More »
CSI Singapore is proud to announce the promotion of Dr. Polly Chen to Associate Professor! Dr. Chen joined CSI Singapore in 2014 as a Principal Investigator. Since then, she has
Congratulations to Dr. Polly Chen on her promotion to Associate Professor! Read More »
Ayako Nakamura-Ishizu 1, Desmond Chin 2, Takayoshi Matsumura 2, Darren Qiancheng Tan 2, Makiko Kashio Mochizuki 1, Deng Jianwen 2, Toshio Suda 3 1Tokyo women’s medical univeristy, Tokyo, Japan. 2National University of Singapore, Singapore, Singapore. 3Kumamoto Univerisity IRCMS, Japan. Abstract Hematopoietic stem cells
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