Job Description

Job Purpose
The mission of the  Cancer Science Institute (National University of Singapore) is to better understand the causes of human cancer across Asia and thereby improve its detection, treatment, and prevention. Our outstanding researchers and exceptional facilities create an energetic environment for ground-breaking science and world-class training.

A Research Assistant position is available immediately in the Yvonne Tay team which studies RNA biology in cancers. You may refer to https://csi.nus.edu.sg/researcher/yvonne-tay/ for more information.

Interested applicants should include the following documents in the job application
1.    Curriculum Vitae (CV)
2.    Summary of past research experience
3.    Description of long-term plans
4.    3 referees including their name, contact information (email) and relationship to applicant

Duties & Responsibilities
Research:
•    Carry out assigned experiments under initial guidance and then independently
•    Organize, preserve, and present the results of the experiments in a logical manner
•    Record all assigned experiments and results properly and systematically
•    Analyse data and design subsequent experimental workflow
•    Assist in supervising, training and guiding attachment/undergraduate students as required

Administrative duties:
•    Assist with lab housekeeping and administrative duties as needed
•    Ensure that standard operating procedures and safety regulations are followed

Qualifications

•    Bachelor’s or Master’s degree in molecular biology, cancer biology, bioinformatics, computational biology, computer science, or related field
•    Interest in pursuing a research career in studying RNA biology in cancer
•    To be a team player with the ability to work collaboratively with other members of the lab.
•    Experience in running projects independently is preferred.
•    Experience in laboratory management is preferred but not essential.
•    Ability to communicate fluently in written and spoken English
•    Knowledge in cell culture and basic molecular biology techniques (western blotting/ RT-PCR etc)
•    Proficiency/ expertise in data analysis (R or equivalent)

Apply here.

Job Description

The Experimental Therapeutics Program seeks a Research Pathologist specializing in solid tumors, particularly breast cancer and nasopharyngeal cancer. The role involves providing pathology-related expertise to support translational research initiatives. This role is an exciting opportunity for a skilled pathologist to contribute to cutting-edge translational research in oncology, enhancing therapeutic strategies for solid tumors through rigorous pathological analysis and collaboration.

The selected candidate will be supporting Prof Lee Soo Chin, more information about her research available at https://csi.nus.edu.sg/researcher/soo-chin-lee/

Key Responsibilities:

1. Research Support:
   • Analyze morphological features of clinical samples for research purposes.
   • Score histological stains, including Immunohistochemistry (IHC), In Situ Hybridization (ISH), and Fluorescence In Situ Hybridization (FISH), in various research projects.
   • Manage and provide pathology-related technologies:
     • Develop and optimize immunohistochemistry assays.
     • Handle tissue arrays.
     • Conduct laser microdissection.
     • Utilize autostainer technology.
     • Operate slide imaging systems.
     • Use advanced microscopy systems.
2. Supervision and Teaching:
   • Supervise and mentor junior staff members.
   • Lead pathology-based projects.
3. Manuscripts and Grants:
   • Assist in the compilation of manuscripts and grant applications.

Qualifications

• Educational Background:
  • MBBS or MD degree is mandatory.
• Experience and Skills:
  • Preference for candidates with several years of experience as a diagnostic histopathologist or surgical pathologist.
  • Hands-on experience in one or more of the following:
    • Immunohistochemistry
    • Laser capture microdissection
    • Construction of tissue microarrays
    • Diagnostic molecular biology techniques and technologies
  • Profound understanding of pathological processes at the tissue level.
  • Ability to work independently.
  • Proficiency in written and spoken English.
  • Excellent writing and reporting abilities.
  • Strong communication skills and a collaborative attitude towards working in a multidisciplinary environment.

Additional Considerations:

• The ideal candidate will demonstrate a strong background in the morphological analysis of tumors, with an ability to integrate pathology insights into broader research contexts.
• Proven track record of developing and implementing novel pathology techniques and contributing to multidisciplinary research teams.

Apply here.

Please also email Kelly Ong your resume after submitting online: kellyong@nus.edu.sg.

Job Description

A Data Manager position is available immediately in Prof Chng Wee Joo’s research group. The selected candidate is responsible for supporting principal clinical investigators in the field of haematologic malignancies, specifically myeloma, stem cell transplantation, and cellular therapy. The primary focus involves both prospective and retrospective data collection for patients.

In addition to direct data management, the position involves active participation in research studies. This includes collecting data from patients enrolled in these studies and maintaining the databases associated with each project. The Data Manager contributes to the overall quality and success of the research initiatives by facilitating smooth data workflows. Furthermore, the role extends to providing necessary data for conference presentations, emphasizing the importance of disseminating research findings to the scientific community. The Data Manager also takes on the responsibility of maintaining up-to-date study status information by submitting essential documents and data to regulatory bodies, such as the Domain Specific Review Board (DSRB) and other relevant registries.

You may refer to https://csi.nus.edu.sg/researcher/wee-joo-chng/ for more information on Prof Chng’s research.

Duties and Responsibilities

Primary Responsibilities and Duties (80%)

1. Collect Clinical Data for Research Studies:
   • Ensure proper consent is obtained from patients enrolled in research studies.
   • Collect clinical data from various reports and clinical notes for accurate data entry.
2. Maintain Stem Cell Transplant (SCT) Research Studies Database:
   • Regularly update and maintain the database for stem cell transplant (SCT) research studies.
   • Assist Clinical Research Coordinator(s) in creating and maintaining site files.
3. Manage Study Status Updates:
   • Submit necessary documents to the Domain Specific Review Board (DSRB) to maintain study status updates.
   • Assist Principal Investigator (PI) in preparing research study protocols and document submissions to DSRB.
4. Coordinate Data-Related Clinical Research:
   • Act as the main coordinator for data-related aspects of clinical research projects.
5. Data Extraction and Reporting:
   • Extract data for analysis and generate reports for publication, conferences, or presentations.
   • Provide required data to the Principal Investigator (PI) for conference presentations.

Secondary Responsibilities and Duties (20%)

1. Analysis and Report Writing Support:
   • Assist with data analysis and contribute to report writing for research projects.
2. Support Value Driven Outcome (VDO) Projects:
   • Work collaboratively with the Value Driven Outcome (VDO) team.
   • Provide data required by the VDO team within given timelines.
3. Ad-Hoc Research Duties:
   • Complete other ad-hoc research duties assigned by the Research Officer (RO) or Principal Investigator (PI) within specified timeframes.

Requirements

Qualification Required and Area of Discipline:

• Bachelor's degree in Biomedical Sciences/Biological Sciences or its equivalent.

Required Competencies and Capabilities:

1. Experience:
   • Preferably has 3-5 years of experience in data management.
   • Experience in Stem Cell Transplantation and/or cellular therapy.
   • Experience in Haematology and/or Oncology related jobs.
2. Technical Skills:
   • Proficient in word processing applications such as Microsoft Word, Excel, and PowerPoint.
   • Statistics skills for data analysis.
3. Interpersonal Skills:
   • Strong interpersonal skills.
   • Ability to work effectively as part of a team.
4. Critical Thinking:
   • Critical thinking skills for problem-solving and decision-making.
5. Learning and Adaptability:
   • Willingness to learn complex medical science concepts and methodologies.
   • Ability to adapt to evolving medical and research environments.
6. Self-Motivation:
   • Self-motivated with the ability to work independently.

Apply here.

Job Description

The mission of Cancer Science Institute (National University of Singapore) is to better understand the causes of human cancer across Asia, and thereby improve its detection, treatment, and prevention. Our outstanding researchers and exceptional facilities create an energetic environment for ground-breaking science and world-class training.

A Research Assistant position is available immediately in the Microscopy and Multiplex Assay Core. The successful candidate will be expected to carry out multiplexed spatial transcriptomic assays, and engage in multidisciplinary collaborative work related to translational research.

You may refer to https://csi.nus.edu.sg/our-research/core-facilities/microscopy-and-multiplex-assays-core/ for more information.

Interested applicants should include the following documents in the job application

1. Curriculum Vitae (CV)
2. Summary of past research experience
3. Description of long-term plans
4. At least 2 referees including their name, contact information (email) and relationship to applicant

Duties And Responsibilities

Research:

• Carry out assigned experiments
• Organize, preserve, and present the results of the experiments in a logical manner
• Record all assigned experiments and results properly and systematically
• Analyse and plan further experiment under guidance
• Assist in supervising, training and guiding attachment/undergraduate students where required

Laboratory:

• To plan and ensure the needs and requirements of the team in terms of consumables
• Ensure that the lab is adequately stocked with clean glassware, minor equipment, chemicals, etc. required for experiments
• Regular checks and maintenance of equipment
• Assemble reagents, chemicals and media that are needed for experiments
• Ensure that standard operating procedures and safety regulations are followed

Administrative duties:

• Plan and ensure that the overall lab administrative needs of the team are met
• Assist the Principal Investigator in tracking his/her grants and other sources of funding
• Procurement of necessary equipment, chemicals, reagents as required by the lab or project
• Maintaining a systematic and proper record of all purchases
• Liaise with vendors and the administrative office to ensure proper purchase requisitions, goods delivery, and prompt payment of supplies
• Any other ad hoc duties as required

Qualifications

• Bachelor’s or Master’s degree in molecular biology, cancer biology, medicine, bioinformatics, computational biology, computer science, or related field
• To be a team player with the ability to work collaboratively with other members of the lab.
• Experience in laboratory management
• Ability to communicate fluently in written and spoken English
• Knowledge in cell culture and basic molecular biology techniques (western blotting/ RT-PCR etc)
• Proficiency/ expertise in data analysis (R or equivalent)

Apply here.

Job Description

Highly motivated and creative postdoctoral candidates are sought to work at the Yang Zhang Lab, Cancer Science Institute of Singapore, School of Computing, and Yong Loo Lin School of Medicine, at National University of Singapore.

Candidates, who are interested in artificial intelligence (AI) and deep machine learning, protein and RNA structural prediction, protein and peptide design and engineering, and/or protein-ligand docking and drug screening, are encouraged to apply. We are particularly interested in the development of new AI-based approaches to cancer therapeutics, including antibody design and discovery, T cell receptor T cell therapy (TCR-T), and peptide-drug conjugate (PDC) cancer therapy. Focus of our laboratory is more on new and creative algorithm/platform developments rather than application of existing programs. Therefore, skills in computational coding and creativity in scientific method design, together with interest in computational cancer medicine, are critical to the position. Previous experience in machine learning will be a plus. More details on our projects can be found at https://zhanggroup.org.

To apply, please send your CV, a brief description of your research interest and plan, and contact information of three professional referees to Prof Yang Zhang (Email: zhang@nus.edu.sg).

Apply here.

Job Description

The Cancer Immunology lab led by Asst. Prof. Jun Siong Low is a new research group at the Cancer Science Institute (CSI). The lab studies human immunology at the interplay between cancer and infection, and uses high-throughput and comprehensive cell- and genetic-based approaches to better understand the phenotype, repertoire and function of T and B cells in cancer patients, with the long-term goal of translating our findings into the clinics.

We are actively seeking highly motivated Research Fellow (Postdoctoral Fellow) to join our efforts and to lead exciting projects in understanding the biology of T and B cell in tumor immunity.

Interested applicants should send the following in one PDF document to lowjs@nus.edu.sg

• Curriculum Vitae (CV)
• Summary of past research experience and research interests
• Description of long-term plans
• 3 referees including their name, contact information (email) and relationship to applicant

Qualifications

Requirements

• PhD degree in relevant fields such as immunology, bioengineering or cancer biology
• Prior experience in bioengineering or CRISPR screening is highly desirable
• Strong track record of research achievement evidenced by high-quality publications in a relevant field
• Skills in working independently and creatively to solve experimental problems

Effective communication and presentation skills, with experience in communicating scientific work including scientific papers, presentations and reports.
https://careers.nus.edu.sg/job-invite/

Apply here.

The position of Postdoctoral Fellow - with an emphasis on computational cancer genomics - is immediately available at the Cancer Science Institute of Singapore (a part of National University of Singapore). The Postdoctoral Fellow will work with the laboratories of Professor Ashok Venkitaraman, on a project studying the evolution of cancer genomes during early steps in carcinogenesis, with the long-term aim to develop better methods for early intervention.

This is an exciting opportunity to deploy expertise in computational biology in an active multidisciplinary environment, working closely with experimental cancer biologists to address major scientific problems.

The Postdoctoral Fellow will apply existing analytic pipelines and devise new algorithms to explore data derived from multiple DNA sequencing technologies (e.g., Illumina & Nanopore) to resolve cancer genome evolution at the clonal level. S/he will also analyse complementary data from other technologies, ranging from single-cell RNAseq to chromatin immunoprecipitation to chromatin accessibility (ATAC-seq), using a variety of novel cellular models established in Professor Venkitaraman’s laboratory. Experimental findings will be explored and validated using clinical genomic datasets.

Please refer to https://csi.nus.edu.sg/researcher/ashok-venkitaraman/ for more information on Professor Ashok Venkitaraman’s research

Interested applicants should include the following documents in the job application

1. Curriculum Vitae (CV)
2. Summary of past research experience
3. Description of long-term plans
4. At least 3 referees including their name, contact information (email) and relationship to applicant

Qualifications

The applicant for this position should possess a PhD in Human genetics, Genomics, Bioinformatics, Computer science, or related fields, with a strong track record of achievement exemplified by publications, is important, as is the required expertise in computational biology listed below. Experience in the methods to be used in the project is desirable.

• Firm understanding of the principles of clonal evolution
• Experience analyzing DNA sequencing data
• Strong Python and/or R programming skills
• Proficient with standard statistical analyses
• Strong publication record
• Excellent written and spoken English

PREFERENCES

• Experience using Amazon Web Services
• Proficiency with Unix-based systems
• Experience with collaborative software development via github/gitlab

Apply here.

The position of Postdoctoral Fellow - with an emphasis on computational cancer genomics - is immediately available at the Cancer Science Institute of Singapore (a part of National University of Singapore). The Postdoctoral Fellow will work with the laboratories of Professor Ashok Venkitaraman, on a project studying the evolution of cancer genomes during early steps in carcinogenesis, with the long-term aim to develop better methods for early intervention.

This is an exciting opportunity to deploy expertise in computational biology in an active multidisciplinary environment, working closely with experimental cancer biologists to address major scientific problems.

The Postdoctoral Fellow will apply existing analytic pipelines and devise new algorithms to explore data derived from multiple DNA sequencing technologies (e.g., Illumina & Nanopore) to resolve cancer genome evolution at the clonal level. S/he will also analyse complementary data from other technologies, ranging from single-cell RNAseq to chromatin immunoprecipitation to chromatin accessibility (ATAC-seq), using a variety of novel cellular models established in Professor Venkitaraman’s laboratory. Experimental findings will be explored and validated using clinical genomic datasets.

Please refer to https://csi.nus.edu.sg/researcher/ashok-venkitaraman/ for more information on Professor Ashok Venkitaraman’s research

Interested applicants should include the following documents in the job application

1. Curriculum Vitae (CV)
2. Summary of past research experience
3. Description of long-term plans
4. At least 3 referees including their name, contact information (email) and relationship to applicant

Duties And Responsibilities

The applicant for this position should possess a PhD in Human genetics, Genomics, Bioinformatics, Computer science, or related fields, with a strong track record of achievement exemplified by publications, is important, as is the required expertise in computational biology listed below. Experience in the methods to be used in the project is desirable.

• Firm understanding of the principles of clonal evolution
• Experience analyzing DNA sequencing data
• Strong Python and/or R programming skills
• Proficient with standard statistical analyses
• Strong publication record
• Excellent written and spoken English

PREFERENCES

• Experience using Amazon Web Services
• Proficiency with Unix-based systems
• Experience with collaborative software development via github/gitlab

Apply here.

Job Description

Cancer Science Institute of Singapore's Core Facility - Genome and Data Analytics Core (GeDac) have multiple genomic data scientist/ bioinformatician positions available. CSI GeDac has built a cloud-based (AWS) platform to facilitate the automated processing and analysis of large cancer genomics datasets.

Successful candidates, in conjunction with software engineering experts, will

1. Build and optimize various components of this platform; and
2. Provide on-demand bioinformatics support for CSI/NUS investigators.

Candidates will have opportunities to apply their biological and technical expertise to diverse, innovative projects while participating in state-of-the-art ML/AI and big data initiatives (e.g. APIs for scalable cancer genome analytics). Candidates will also have numerous opportunites to expand their skills and networks by collaborating with multiple local and multinational industrial stakeholders. Although candidates are expected to have a variety of bioinformatics skills, we are particularly keen to identify experts in RNA-seq, single cell RNA-seq, and ChIP/ATAC-seq technologies. Overall, these positions provide a unique opportunity to work with a large, diverse team to drive discoveries in cancer genomics and enhance precision oncology.

Qualifications

Requirements

• Masters or Ph.D. in genetics, genomics, bioinformatics, computational biology, data science, or related fields
• Solid foundation in biology and genomics, particularly in cancer
• Experience processing and analyzing high-throughput sequencing data
• Appreciable Python and/or R programming skills
• Familiarity with cluster (including HPC) and/or cloud computing
• Excellent written and spoken English

Preferences

• Authorship on scientific publications
• Software development experience
• Experience with collaborative software development via github/gitlab.

Apply here.