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Principal Investigators

Translational research in oncology, focusing on immunotherapy
RNA alterations in cancer and development of RNA-based therapeutics
Our lab studies ways to overcome high-risk cancers
Engineering-based approaches to improve precision and personalised cancer treatment
How cellular pathways maintain genomic integrity in response to intrinsic topological stress
Development of novel treatments for cancers
Regulation of stomach epithelial stem cells in homeostasis and cancer
How the immune system recognizes chemotherapy treated cancer cells
Protemics of non-coding elements in cancer
Biomolecular condensates in cancer biology and its modulation for the development of cancer therapeutics
Novel therapeutics and predictive biomarkers in breast cancer
Immune responses to cancer
Cancer genome data science at scale
Translational approaches for targeting cellular energetics and cell states in cancer
Development of biomarkers and novel anti-cancer therapeutic agents focusing on gynaecological cancers
Genetic analysis of Asian-prevalent malignancies to identify new biomarkers and drug targets
Understanding RNA biology and developing RNA-based biomarkers and drugs
(1) Gene regulation and cancer; (2) the role of the oncofetal protein SALL4 in cancer
Deciphering the mechanisms underlying cancer susceptibility to intercept cancer evolution
AI-based protein structure prediction & protein design, & their application to cancer therapeutics development

Special Fellows

Understanding causes and effects of DNA damage and genome fragility