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Congratulations to Prof. Chng Wee Joo for being the first Asian recipient of the prestigious 2020 Brian G.M Durie Outstanding Achievement Award!

Warmest congratulations to CSI Deputy Director and Senior Principal Investigator, Prof. Chng Wee Joo for being awarded the 2020 Brian G.M Durie Outstanding Achievement Award! Prof. Chng is the first …

Congratulations to Prof. Chng Wee Joo for being the first Asian recipient of the prestigious 2020 Brian G.M Durie Outstanding Achievement Award! Read More »

CSI Principal Investigator and Senior Research Scientist Receive Awards at the Asian Fund for Cancer Research’s (AFCR) 2021 BRACE Award Venture Competition

Congratulations to A/Prof. Edward Kai-Hua Chow and Dr. Bee Hui Liu, who have recently won awards at the Asian Fund for Cancer Research’s (AFCR) 2021 BRACE Award Venture Competition, a …

CSI Principal Investigator and Senior Research Scientist Receive Awards at the Asian Fund for Cancer Research’s (AFCR) 2021 BRACE Award Venture Competition Read More »

Phase Ib/II Dose Expansion Study of Lenvatinib Combined with Letrozole in Post-Menopausal Women with Hormone Receptor Positive Breast Cancer (Clin Cancer Res, Apr 22)

Joline S J Lim 1, Andrea L A Wong 2, Samuel G W Ow 1, Natalie Y L Ngoi 3, Gloria H J Chan 4, Yvonne L E Ang 5, Wan Qin Chong 6, Siew Eng Lim 4, Yi Wan Lim 6, Matilda Lee 4, Joan R E Choo 7, Hon Lyn …

Phase Ib/II Dose Expansion Study of Lenvatinib Combined with Letrozole in Post-Menopausal Women with Hormone Receptor Positive Breast Cancer (Clin Cancer Res, Apr 22) Read More »

ADARs act as potent regulators of circular transcriptome in cancer (Nat Commun, Mar 2022)

Haoqing Shen 1 2, Omer An 1, Xi Ren 1, Yangyang Song 1, Sze Jing Tang 1, Xin-Yu Ke 1 2, Jian Han 1, Daryl Jin Tai Tay 1, Vanessa Hui En Ng 1, Fernando Bellido Molias 1, Priyankaa Pitcheshwar 1 2, Ka Wai Leong 1, Ker-Kan Tan 3 4 5, Henry Yang 1, Leilei Chen 6 7 8 Affiliations 1Cancer Science Institute of Singapore, National …

ADARs act as potent regulators of circular transcriptome in cancer (Nat Commun, Mar 2022) Read More »

Clinical Translation of Patient-Derived Tumour Organoids- Bottlenecks and Strategies. (Biomark Res, Mar 22)

Malia Alexandra Foo # 1, Mingliang You # 2 3, Shing Leng Chan 1 4, Gautam Sethi 5 6, Glenn K Bonney 4 5, Wei-Peng Yong 1 7, Edward Kai-Hua Chow 1 5 6, Eliza Li Shan Fong 1 8, Lingzhi Wang 9 10 11, Boon-Cher Goh 12 13 14 15 Affiliations 1Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore. 2Hangzhou …

Clinical Translation of Patient-Derived Tumour Organoids- Bottlenecks and Strategies. (Biomark Res, Mar 22) Read More »

p53-NEIL1 co-abnormalities induce genomic instability and promote synthetic lethality with Chk1 inhibition in multiple myeloma having concomitant 17p13(del) and 1q21(gain). (Oncogene, Feb 2022)

Phaik Ju Teoh 1 2, Omer An 3, Tae-Hoon Chung 3, Thamil Vaiyapuri 4, Anandhkumar Raju 4, Michal M Hoppe 3, Sabrina H M Toh 3, Wilson Wang 5 6, Ming Chun Chan 5 6, Melissa J Fullwood 3, Anand D Jeyasekharan 7 3 8 9, Vinay Tergaonkar 4, Leilei Chen 3, Henry Yang 3, Wee Joo Chng 7 3 8 9 Affiliations 1Department of Medicine, Yong Loo …

p53-NEIL1 co-abnormalities induce genomic instability and promote synthetic lethality with Chk1 inhibition in multiple myeloma having concomitant 17p13(del) and 1q21(gain). (Oncogene, Feb 2022) Read More »

MYC overexpression leads to increased chromatin interactions at superenhancers and MYC binding sites. (Genome Res, Feb 2022)

Yi Xiang See 1, Kaijing Chen 1, Melissa J Fullwood 2 Affiliations 1Nanyang Technological University, Cancer Science Institute of Singapore, National University of Singapore. 2Nanyang Technological University, Cancer Science Institute of Singapore, National University of …

MYC overexpression leads to increased chromatin interactions at superenhancers and MYC binding sites. (Genome Res, Feb 2022) Read More »