Screenshot 2024-03-25 at 5.58.33 PM

Translational Exchange (TREX) club

The Translational Exchange (TREX) club is setup as a joint initiative between the Cancer Science Institute of Singapore (CSI Singapore), NUS Centre for Cancer Research (N2CR) and the National University Cancer Institute, Singapore (NCIS), to facilitate the development of meaningful collaborations between clinicians and basic scientists at the three institutes, have open dialogues on clinical/scientific questions, as well as, encourage greater understanding between clinical/scientific questions to achieve their research goals in a collaborative fashion.

This is a targeted tumour specific group meeting of main interest to CSI Singapore, NCIS and N2CR, and specific clinicians and scientists (but open to all faculty) are invited. The clinicians will present available datasets, tissue collections, unusual responders/non-responders while the scientists will present potential leads, markers, techniques for translational work. At the end of each meeting, a collaborative project will be selected by the attendees for funding with varying quantum of between SGD 30,000 – SGD 40,000 for 1 year.

Key Research Initiatives

t cell

Paradox in a T-cell Lymphoma Aggressive Malignancy, Low Genomic Complexity

TREX Club CSI Scientist: Jason Pitt

TREX Club NCIS Clinician: Ng Siok Bian

Tumour-Specific Theme: All

download

ncRNA Regulation of the Tumor Immune Microenvironment of Peritoneal Metastases

TREX Club CSI Scientist: Yvonne Tay

TREX Club NCIS Clinician: Raghav Sundar

Tumour-Specific Theme: All

download (1)

Quantitative Proteomics Profiles Combined with Telomere Maintenance Mechanism in Liposarcoma

TREX Club CSI Scientist: Dennis Kappei

TREX Club NCIS Clinician: Victor Lee

Tumour-Specific Theme: Solid Malignancies

images

Quantitative Proteomics Profiling of Hormone Receptor-Positive, HER2-negative Breast from FFPE Samples to Elucidate Differential Profiling Between Good and Poor Responders to CDK4/6 Inhibitor Therapy 

TREX Club CSI Scientist: Dennis Kappei

TREX Club NCIS Clinician: Joline Lim

Tumour-Specific Theme: Haemotology - Oncology 

download (3)

Integrated Stress Response in HPV-positive Head and Neck Tumors

TREX Club CSI Scientist: Anthony Khong

TREX Club NCIS Clinician: Oon Ming Liang

Tumour-Specific Theme: Pathology 

depositphotos_57357703-stock-photo-cancer-cell

Spatial Insights into Immune Landscapes: Mapping a Lymphoid Tissue Atlas with Transcriptomics and Proteomics

TREX Club CSI Scientist: Dennis Kappei

TREX Club NCIS Clinician: Ng Siok Bian

Tumour-Specific Theme: Pathology 

images (1)

Evaluating T-Cell Responses Following Cancer Vaccine Treatment in Gastric Cancer Patients

TREX Club CSI Scientist: Low Jun Siong

TREX Club NCIS Clinician: Yong Wei Peng

Tumour-Specific Theme: Pathology