Kar-Tong Tan 1 2 3, Ling-Wen Ding 4, Chan-Shuo Wu 1, Daniel G Tenen 5 6, Henry Yang 5 7 Affiliations 1Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore. 2Biological and Biomedical Sciences Program, Division of Medical Sciences, Harvard Medical …
Our bodies constantly encounter oxidants from our diet and metabolism. Oxidative stress is thought to speed up ageing, and increase the risk of diseases like cancer or dementia. However, there …
Nisha Padmanabhan 1, Huang Kie Kyon # 1, Arnoud Boot # 2, Kevin Lim 1, Supriya Srivastava 3, Shuwen Chen 4, Zhiyuan Wu 5, Hyung-Ok Lee 6, Vineeth T Mukundan 7, Charlene Chan 7, Yarn Kit Chan 1, Ong Xuewen 1, Jason J Pitt 7, Zul Fazreen Adam Isa 1, Manjie Xing 1, Ming Hui Lee 1, Angie Lay Keng Tan 1, Shamaine Ho Wei Ting 1, Micah …
Chong Yang 1, Mitsuhiro Endoh 1 2, Darren Q Tan 1, Ayako Nakamura-Ishizu 1 3, Yuji Takihara 1, Takayoshi Matsumura 1, Toshio Suda 1 4 Affiliations 1Cancer Science Institute of Singapore, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. 2Department of Pluripotent …
Phyllis S Y Chong # 1, Jing Yuan Chooi # 2, Julia S L Lim 2 3, Sabrina Hui Min Toh 3, Tuan Zea Tan 3, Wee-Joo Chng 1 3 4 Affiliations 1Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. …
Gene transcription is controlled largely by transcription factors that bind to enhancers, which are regions of the DNA that loop over to genes to activate them. While silencers have been …
Researchers Identify Looping Silencers as a Promising Target for Cancer Treatment Read More »
The pathways that control the behaviour of diseased cells involve complex interactions between large molecules like proteins. Protein-protein interactions (PPIs) represent a vast repertoire of potential targets for new drugs …
Development of novel Camsirubicin analog expands Monopar’s therapeutic pipeline WILMETTE, Ill., June 03, 2021 (GLOBE NEWSWIRE) — Monopar Therapeutics Inc. (Nasdaq: MNPR), a clinical-stage biopharmaceutical company primarily focused on developing …
Jiayi Weng 1, Xiaoqiang Xiang 2, Lingwen Ding 3, Andrea Li-Ann Wong 4, Qi Zeng 5, Gautam Sethi 6, Lingzhi Wang 7, Soo Chin Lee 8, Boon Cher Goh 9 Affiliations 1Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore; Department of Medicine, Yong …
Daryl Jin Tai Tay 1, Yangyang Song 1, Boya Peng 2, Tan Boon Toh 3, Lissa Hooi 1, Desiree-Faye Kaixin Toh 4, HuiQi Hong 5, Sze Jing Tang 1, Jian Han 1, Wei Liang Gan 1, Tim Hon Man Chan 1, Manchugondanahalli S Krishna 4, Kiran M Patil 4, Manikantha Maraswami 4, Teck Peng Loh 4, Yock Young Dan 6, Lei Zhou 7, Glenn …
