It’s a Wrap! CanCycle 2023
After 2 months of fundraising and cycling, CanCycle 2023 has officially come to an end! The Closing Ceremony took place last Saturday, 11 Feb 2023 at NUS. Our participants, supporters, …
Latest Happenings
[Meta-Analysis] A Pooled Analysis of Outcomes According to Cytogenetic Abnormalities in Patients Receiving Ixazomib- vs Placebo-based Therapy for Multiple Myeloma (Blood Cancer J., Jan 23)
Wee-Joo Chng 1 2, Sagar Lonial 3, Gareth J Morgan 4, Shinsuke Iida 5, Philippe Moreau 6, Shaji K Kumar 7, Philip Twumasi-Ankrah 8, Miguel Villarreal 8, Ajeeta B Dash 8, Alexander Vorog 8, Xiaoquan Zhang 8, Kaveri Suryanarayan 8, Richard Labotka 8, Meletios A Dimopoulos 9, S Vincent Rajkumar 7 Affiliations 1Department of Hematology-Oncology, National University Cancer Institute, Singapore, …
[Meta-Analysis] FAM3C in Circulating Tumor-derived Extracellular Vesicles Promotes Non-small Cell Lung Cancer Growth in Secondary Sites (Theranostics, Jan 23)
Win Lwin Thuya 1, Li Ren Kong 1 2 3, Nicholas L Syn 1 4, Ling-Wen Ding 1 5, Esther Sok Hwee Cheow 1, Regina Tong Xin Wong 1, Tingting Wang 1, Robby Miguel Wen-Jing Goh 1, Hongyan Song 1, Migara K Jayasinghe 2, Minh Tn Le 2 3, Jian Cheng Hu 3, Wei-Peng Yong 1 3 6, Soo-Chin Lee 1 3 6, Andrea Li-Ann Wong 1 3 6, Gautam Sethi 2 3, Huynh …
De Novo Protein Fold Design Through Sequence-independent Fragment Assembly Simulations (Proc. Natl. Acad. Sci. U S A, Jan 23)
Robin Pearce 1, Xiaoqiang Huang 1, Gilbert S Omenn 1 2 3 4, Yang Zhang 1 5 6 7 Affiliations 1Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109. 2Department of Internal Medicine, University of Michigan, Ann Arbor, MI …
Computational design of novel protein folds
CSI Singapore’s newest staff addition, Professor Yang Zhang, recently led a group of researchers in creating a software, called FoldDesign, which can design protein structures without utilizing known scaffolds from …
Stromal reprogramming through dual PDGFR?/? blockade boosts the efficacy of anti-PD-1 immunotherapy in fibrotic tumors [Cancer Res, Dec 2022]
In collaboration with CSI Singapore’s Prof. Patrick Tan, a group of researchers investigated the mechanisms by which the stroma manipulates the immune microenvironment and facilitates cancer progression and immune evasion. …
Deciphering Colorectal Cancer Genetics through Multi-omic Analysis of 100,204 Cases and 154,587 Controls of European and East Asian Ancestries [Nat Genet, Dec 2022]
In collaboration with CSI Singapore’s Prof. Lee Soo Chin, a group of researchers conducted a genome-wide association study meta-analysis of 100,204 colorectal cancer (CRC) cases and 154,587 controls of European …
Real-world outcomes from use of CDK4/6 inhibitors in the management of advanced/metastatic breast cancer in Asia [Ther Adv Med Oncol, Dec 2022]
A group of researchers, led by CSI Singapore’s Prof. Lee Soo Chin, evaluated the clinical outcomes for combinations of cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) with anti-oestrogen therapy for treatment of …
Congratulations A/Prof. Tam Wai Leong on the NRF Investigatorship 2023!
Congratulations to CSI Singapore’s A/Prof Tam Wai Leong on being awarded the NRF Investigatorship for 2023! The NRF Investigatorship is awarded by the National Research Foundation; which aims to develop …
Congratulations A/Prof. Tam Wai Leong on the NRF Investigatorship 2023! Read More »
CSI Singapore @ ASH 2022
CSI Singapore recently exhibited at the 64th ASH Annual Meeting and Exposition held in New Orleans, Louisiana, with both a showcase booth as well as student and staff presentations. Presenters …