Xin-Yu Ke 1 2, Ye Chen 3, Valarie Yu-Yan Tham 1, Ruby Yu-Tong Lin 1, Pushkar Dakle 1, Kassoum Nacro 4, Mark Edward Puhaindran 5 6 7, Peter Houghton 8, Angela Pang 5, Victor Kwanmin Lee 9, Ling-Wen Ding 10, Sigal Gery 11, Jeffrey Hill 12, Leilei Chen 1 2, Liang Xu 13, H Phillip Koeffler 1 5 11 Author Information 1Cancer Science Institute of Singapore, National …

MNK1 and MNK2 enforce expression of E2F1, FOXM1, and WEE1 to drive soft tissue sarcoma. (Oncogene, Feb 2021) Read More »

Qiling Zhou 1 2, Miao Yu 3, Roberto Tirado-Magallanes 1, Bin Li 4, Lingshi Kong 1, Mingrui Guo 1 2, Zi Hui Tan 1, Sanghoon Lee 1 5, Li Chai 6, Akihiko Numata 1 7, Touati Benoukraf 1 8, Melissa Jane Fullwood 1 9 10, Motomi Osato 1, Bing Ren 4 11, Daniel G Tenen 12 13 Author Information 1Cancer Science Institute of Singapore, National University of Singapore, …

ZNF143 mediates CTCF-bound promoter-enhancer loops required for murine hematopoietic stem and progenitor cell function. (Nat Commun, Jan 2021) Read More »

Dexter Kai Hao Thng 1, Tan Boon Toh 2, Edward Kai-Hua Chow 3 Author Information 1Cancer Science Institute of Singapore, National University of Singapore, Singapore. 2The N.1 Institute for Health, National University of Singapore, Singapore; …

Capitalizing on Synthetic Lethality of MYC to Treat Cancer in the Digital Age. (Trends Pharmacol Sci, Jan 2021) Read More »

Guo-Liang Chew 1, Marie Bleakley 2, Robert K Bradley 3 4 5, Harmit S Malik 4 6, Steven Henikoff 4 6, Antoine Molaro 7 8, Jay Sarthy 9 Author Information 1The Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore. 2Clinical Research Division, Fred Hutchinson Cancer …

Short H2A histone variants are expressed in cancer. (Nat Commun, Jan 2021) Read More »

Yi Bao 1 2, Gokce Oguz 2, Wee Chyan Lee 2, Puay Leng Lee 2, Kakaly Ghosh 2, Jiayao Li 3, Panpan Wang 3, Peter E Lobie 1 4, Sidse Ehmsen 5, Henrik J Ditzel 5 6, Andrea Wong 7, Ern Yu Tan 8, Soo Chin Lee 9 10, Qiang Yu 11 12 13 Author Information 1Cancer Science Institute of Singapore, Yong Loo …

EZH2-mediated PP2A inactivation confers resistance to HER2-targeted breast cancer therapy. (Nat Commun, Nov 2020) Read More »

Yun Wei Shermane Lim 1, Xiaoqiang Xiang 2, Manoj Garg 3, Minh Tn Le 4, Andrea Li-Ann Wong 5, Lingzhi Wang 6, Boon-Cher Goh 7 Author Information 1Cancer Science Institute of Singapore, National University of Singapore, Singapore, 117599, Singapore; Institute for Digital Medicine …

The double-edged sword of H19 lncRNA: Insights into cancer therapy (Cancer Lett, Nov 2020) Read More »

Junichi Matsuo 1, Daisuke Douchi 1 2, Khine Myint 1, Naing Naing Mon 1, Akihiro Yamamura 1 2, Kazuyoshi Kohu 1, Dede Liana Heng 1, Sabirah Chen 1, Nur Astiana Mawan 1, Napat Nuttonmanit 1, Ying Li 1, Supriya Srivastava 3, Shamaine Wei Ting Ho 1 4, Nicole Yee Shin Lee 5, Hong Kai Lee 5, Makoto Adachi 6, Atsushi Tamura 7 8 9, Jinmiao Chen 5, Henry Yang 1, Ming Teh 10, Jimmy Bok-Yan …

Iqgap3-Ras axis drives stem cell proliferation in the stomach corpus during homoeostasis and repair. (Gut, Dec 2020) Read More »

Akihiko Numata 1 2, Hui Si Kwok 1, Qi-Ling Zhou 1, Jia Li 1, Roberto Tirado-Magallanes 1, Vladimir Espinosa Angarica 1, Rebecca Hannah 3 4, Jihye Park 5, Chelsia Qiuxia Wang 1, Vaidehi Krishnan 1, Deepa Rajagopalan 1, Yanzhou Zhang 1, Siqin Zhou 1, Robert S Welner 6, Motomi Osato 1, Sudhakar Jha 1, Stefan K Bohlander 7, Berthold Göttgens 3 4, Henry Yang 1, Touati Benoukraf 1 8, John W Lough 9, Deepak Bararia 1 10, Daniel G …

Lysine acetyltransferase Tip60 is required for hematopoietic stem cell maintenance. (Blood, Oct 2020) Read More »

Zhi Hao Kwok 1, Bin Zhang 2, Xiao Hong Chew 2, Jia Jia Chan 2, Velda Teh 2, Henry Yang 2, Dennis Kappei 2, Yvonne Tay 3 Author Information 1Cancer Science Institute of Singapore. 2Cancer Science Institute of Singapore, National University of Singapore. 3Cancer Science …

Systematic analysis of intronic microRNAs reveals cooperativity within the multi-component FTX locus to promote colon cancer development. (Cancer Res, Nov 2020) Read More »