Latest Happenings

Global analysis of RNA-binding proteins identifies a positive feedback loop between LARP1 and MYC that promotes tumorigenesis. (Cell Mol Life Sci, Feb 2022)

2022, Latest Happenings, Research /

Ng Desi # 1 2, Qing Yun Tong # 1, Velda Teh # 1, Jia Jia Chan # 1, Bin Zhang # 1, Hossein Tabatabaeian 1, Hui Qing Tan 3, Katannya Kapeli 3, Wenhao Jin 3, Chun You Lim 1, Zhi Hao Kwok 1 4, Hwee Tong Tan 2, Shi Wang 5, Bei-En Siew 6, Kuok-Chung Lee 7, Choon-Seng Chong 6 7, Ker-Kan Tan 6 7, Henry Yang 1 2, Dennis Kappei 1 2, Gene W Yeo 3 8, Maxey Ching Ming […]

Global analysis of RNA-binding proteins identifies a positive feedback loop between LARP1 and MYC that promotes tumorigenesis. (Cell Mol Life Sci, Feb 2022) Read More »

p53-NEIL1 co-abnormalities induce genomic instability and promote synthetic lethality with Chk1 inhibition in multiple myeloma having concomitant 17p13(del) and 1q21(gain). (Oncogene, Feb 2022)

2022, Latest Happenings /

Phaik Ju Teoh 1 2, Omer An 3, Tae-Hoon Chung 3, Thamil Vaiyapuri 4, Anandhkumar Raju 4, Michal M Hoppe 3, Sabrina H M Toh 3, Wilson Wang 5 6, Ming Chun Chan 5 6, Melissa J Fullwood 3, Anand D Jeyasekharan 7 3 8 9, Vinay Tergaonkar 4, Leilei Chen 3, Henry Yang 3, Wee Joo Chng 7 3 8 9 Affiliations 1Department of Medicine, Yong Loo

p53-NEIL1 co-abnormalities induce genomic instability and promote synthetic lethality with Chk1 inhibition in multiple myeloma having concomitant 17p13(del) and 1q21(gain). (Oncogene, Feb 2022) Read More »

MiR-138 is a Potent Regulator of the Heterogenous MYC Transcript Population in Cancers. (Oncogene, Dec 2021)

2022, Latest Happenings, Research /

Ng Desi 1 2, Velda Teh 1, Qing Yun Tong 1, Chun You Lim 1, Hossein Tabatabaeian 1, Xiao Hong Chew 1, Avencia Sanchez-Mejias 1 3, Jia Jia Chan 1, Bin Zhang 1, Priyankaa Pitcheshwar 1, Bei-En Siew 4, Shi Wang 5, Kuok-Chung Lee 6, Choon-Seng Chong 4 6, Wai-Kit Cheong 6, Bettina Lieske 4 6, Ian Jse-Wei Tan 6, Ker-Kan Tan 4 6, Yvonne Tay 7 8 Affiliations 1Cancer Science Institute of

MiR-138 is a Potent Regulator of the Heterogenous MYC Transcript Population in Cancers. (Oncogene, Dec 2021) Read More »

ChIP-AP: An Integrated Analysis Pipeline for Unbiased ChIP-seq Analysis. (Brief Bioinform, Jan 2022)

2022, Latest Happenings, Research /

Jeremiah Suryatenggara 1, Kol Jia Yong 1 2, Danielle E Tenen 3, Daniel G Tenen 1 4, Mahmoud A Bassal 1 4 Affiliations 1Cancer Science Institute of Singapore, National University of Singapore, Singapore, 117599, Singapore. 2Department of Biochemistry, Yong Loo Lin School

ChIP-AP: An Integrated Analysis Pipeline for Unbiased ChIP-seq Analysis. (Brief Bioinform, Jan 2022) Read More »

A Point Mutation R122C in RUNX3 Promotes the Expansion of Isthmus Stem Cells and Inhibits Their Differentiation in the Stomach. (Cell Mol Gastroenterol Hepatol, Jan 2022)

2022, Latest Happenings, Research /

Daisuke Douchi 1, Akihiro Yamamura 1, Junichi Matsuo 2, Jung-Won Lee 3, Napat Nuttonmanit 2, Yi Hui Melissa Lim 2, Kazuto Suda 4, Mitsuhiro Shimura 1, Sabirah Chen 2, ShuChin Pang 2, Kazuyoshi Kohu 2, Mari Kaneko 5, Hiroshi Kiyonari 5, Atsushi Kaneda 6, Hideyuki Yoshida 7, Ichiro Taniuchi 8, Motomi Osato 2, Henry Yang 2, Michiaki Unno 9, Jimmy Bok-Yan So 10, Khay Guan Yeoh 11, Linda Shyue Huey Chuang 12, Suk-Chul Bae 3, Yoshiaki

A Point Mutation R122C in RUNX3 Promotes the Expansion of Isthmus Stem Cells and Inhibits Their Differentiation in the Stomach. (Cell Mol Gastroenterol Hepatol, Jan 2022) Read More »

Immunohistochemistry Study of Tumor Vascular Normalization and Anti-Angiogenic Effects of Sunitinib Versus Bevacizumab Prior to Dose-Dense Doxorubicin/Cyclophosphamide Chemotherapy in HER2-Negative Breast Cancer. (Breast Cancer Res Treat, Dec 2021)

2021, Latest Happenings, Research /

Kritika Yadav 1 2, Joline Lim 3, Joan Choo 3, Samuel Guan Wei Ow 3, Andrea Wong 3, Matilda Lee 3, Ching Wan Chan 4, Mikael Hartman 4, Siew Eng Lim 3, Natalie Ngoi 3, Siau Wei Tang 4, Yvonne Ang 3, Gloria Chan 3, Wan Qin Chong 3, Hon Lyn Tan 3, Sing Huang Tan 3, Boon Cher Goh 2 3, Soo Chin Lee 5 6 Affiliations

Immunohistochemistry Study of Tumor Vascular Normalization and Anti-Angiogenic Effects of Sunitinib Versus Bevacizumab Prior to Dose-Dense Doxorubicin/Cyclophosphamide Chemotherapy in HER2-Negative Breast Cancer. (Breast Cancer Res Treat, Dec 2021) Read More »

Super enhancer-mediated upregulation of HJURP promotes growth and survival of t(4;14)-positive multiple myeloma (Cancer Res, Dec 2021)

2021, Latest Happenings, Research /

Yunlu Jia 1, Jianbiao Zhou 2, Tze King Tan 3, Tae-Hoon Chung 2, Yong Xia Chen 4, Jing-Yuan Chooi 2, Takaomi Sanda 3, Melissa Jane Fullwood 5, Sinan Xiong 2, Sabrina Hui Min Toh 6, Kalpnaa Balan 2, Regina WanJu Wong 7, Julia S L Lim 8, Enfan Zhang 9, Zhen Cai 9, Peng Shen 10, Wee Joo Chng 11 Affiliations 1Medical oncology,

Super enhancer-mediated upregulation of HJURP promotes growth and survival of t(4;14)-positive multiple myeloma (Cancer Res, Dec 2021) Read More »

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