Our bodies constantly encounter oxidants from our diet and metabolism. Oxidative stress is thought to speed up ageing, and increase the risk of diseases like cancer or dementia. However, there […]
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Chong Yang 1, Mitsuhiro Endoh 1 2, Darren Q Tan 1, Ayako Nakamura-Ishizu 1 3, Yuji Takihara 1, Takayoshi Matsumura 1, Toshio Suda 1 4 Affiliations 1Cancer Science Institute of Singapore, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. 2Department of Pluripotent
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Gene transcription is controlled largely by transcription factors that bind to enhancers, which are regions of the DNA that loop over to genes to activate them. While silencers have been
Researchers Identify Looping Silencers as a Promising Target for Cancer Treatment Read More »
The pathways that control the behaviour of diseased cells involve complex interactions between large molecules like proteins. Protein-protein interactions (PPIs) represent a vast repertoire of potential targets for new drugs
Development of novel Camsirubicin analog expands Monopar’s therapeutic pipeline WILMETTE, Ill., June 03, 2021 (GLOBE NEWSWIRE) — Monopar Therapeutics Inc. (Nasdaq: MNPR), a clinical-stage biopharmaceutical company primarily focused on developing
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Liang Xu 1 2, Ye Chen 1, Yulun Huang 3 4 5, Edwin Sandanaraj 6 7, John S Yu 8, Ruby Yu-Tong Lin 9, Pushkar Dakle 9, Xin-Yu Ke 9, Yuk Kien Chong 6, Lynnette Koh 6 10, Anand Mayakonda 9, Kassoum Nacro 11, Jeffrey Hill 12, Mo-Li Huang 9 13, Sigal Gery 14, See Wee Lim 6, Zhengyun Huang 15, Ying Xu 15, Jianxiang Chen 16 17 18, Longchuan Bai 19 20, Shaomeng Wang 19 20 21 22, Hiroaki Wakimoto 23, Tseng Tsai Yeo 24, Beng Ti
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