Research

Determinants of Response to Daratumumab in Epstein-Barr Virus-Positive Natural Killer and T-Cell Lymphoma. (J Immunother Cancer, Jul 2021)

Nurulhuda Mustafa 1 2, Adina Huey Fang Nee 2, Jing Yuan Chooi 3, Sabrina Hui Min Toh 2, Tae-Hoon Chung 2, Viknesvaran Selvarajan 4, Shuangyi Fan 4, Siok Bian Ng 2 4 5, Michelle Poon 6, Esther Chan 6, Joanne Lee 6, Yen Lin Chee 6, Anand D Jeyasekharan 2 6, Longen Zhou 7, Jennifer Yang 7, Wee Joo Chng 3 2 6 Affiliations 1Department of Medicine, […]

Determinants of Response to Daratumumab in Epstein-Barr Virus-Positive Natural Killer and T-Cell Lymphoma. (J Immunother Cancer, Jul 2021) Read More »

Chromatin Interaction Neural Network (ChINN): A Machine Learning-Based Method for Predicting Chromatin Interactions from DNA Sequences. (Genome Biol, Aug 2021)

Fan Cao # 1, Yu Zhang # 2, Yichao Cai # 1, Sambhavi Animesh 1, Ying Zhang 1, Semih Can Akincilar 3, Yan Ping Loh 1, Xinya Li 4, Wee Joo Chng 1 5 6, Vinay Tergaonkar 3 7, Chee Keong Kwoh 2, Melissa J Fullwood 8 9 10 Affiliations 1Cancer Science Institute of Singapore, National University of Singapore, 14 Medical

Chromatin Interaction Neural Network (ChINN): A Machine Learning-Based Method for Predicting Chromatin Interactions from DNA Sequences. (Genome Biol, Aug 2021) Read More »

Highly recurrent CBS epimutations in gastric cancer CpG island methylator phenotypes and inflammation. (Genome Biol, Jun 2021)

Nisha Padmanabhan 1, Huang Kie Kyon # 1, Arnoud Boot # 2, Kevin Lim 1, Supriya Srivastava 3, Shuwen Chen 4, Zhiyuan Wu 5, Hyung-Ok Lee 6, Vineeth T Mukundan 7, Charlene Chan 7, Yarn Kit Chan 1, Ong Xuewen 1, Jason J Pitt 7, Zul Fazreen Adam Isa 1, Manjie Xing 1, Ming Hui Lee 1, Angie Lay Keng Tan 1, Shamaine Ho Wei Ting 1, Micah

Highly recurrent CBS epimutations in gastric cancer CpG island methylator phenotypes and inflammation. (Genome Biol, Jun 2021) Read More »

Mitochondria transfer from early stages of erythroblasts to their macrophage niche via tunnelling nanotubes. (Br J Haematol, Jun 2021)

Chong Yang 1, Mitsuhiro Endoh 1 2, Darren Q Tan 1, Ayako Nakamura-Ishizu 1 3, Yuji Takihara 1, Takayoshi Matsumura 1, Toshio Suda 1 4 Affiliations 1Cancer Science Institute of Singapore, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. 2Department of Pluripotent

Mitochondria transfer from early stages of erythroblasts to their macrophage niche via tunnelling nanotubes. (Br J Haematol, Jun 2021) Read More »

SMARCA2 Is a Novel Interactor of NSD2 and Regulates Prometastatic PTP4A3 through Chromatin Remodeling in t(4;14) Multiple Myeloma. (Cancer Res, May 2021)

Phyllis S Y Chong # 1, Jing Yuan Chooi # 2, Julia S L Lim 2 3, Sabrina Hui Min Toh 3, Tuan Zea Tan 3, Wee-Joo Chng 1 3 4 Affiliations 1Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

SMARCA2 Is a Novel Interactor of NSD2 and Regulates Prometastatic PTP4A3 through Chromatin Remodeling in t(4;14) Multiple Myeloma. (Cancer Res, May 2021) Read More »

Monopar Announces New Drug Candidate, MNPR-202, and Enters into Collaboration Agreement with the National University of Singapore for Preclinical Evaluation in Cancer

Development of novel Camsirubicin analog expands Monopar’s therapeutic pipeline WILMETTE, Ill., June 03, 2021 (GLOBE NEWSWIRE) — Monopar Therapeutics Inc. (Nasdaq: MNPR), a clinical-stage biopharmaceutical company primarily focused on developing

Monopar Announces New Drug Candidate, MNPR-202, and Enters into Collaboration Agreement with the National University of Singapore for Preclinical Evaluation in Cancer Read More »

Extracellular Vesicles, the Cornerstone of Next-Generation Cancer Diagnosis? (Semin Cancer Biol, May 2021)

Jiayi Weng 1, Xiaoqiang Xiang 2, Lingwen Ding 3, Andrea Li-Ann Wong 4, Qi Zeng 5, Gautam Sethi 6, Lingzhi Wang 7, Soo Chin Lee 8, Boon Cher Goh 9 Affiliations 1Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore; Department of Medicine, Yong

Extracellular Vesicles, the Cornerstone of Next-Generation Cancer Diagnosis? (Semin Cancer Biol, May 2021) Read More »