Ferrer M, Mourikis N, Davidson EE, Kleeman SO, Zaccaria M, Habel J, Rubino R, Gao Q, Flint TR, Young L, Connell CM, Lukey MJ, Goncalves MD, White EP, Venkitaraman AR, …

Ketogenic Diet Promotes Tumor Ferroptosis but Induces Relative Corticosterone Deficiency that Accelerates Cachexia (Cell Metab., Jun 2023) Read More »

Zhou J, Toh SH, Tan TK, Balan K, Lim JQ, Tan TZ, Xiong S, Jia Y, Ng SB, Peng Y, Jeyasekharan AD, Fan S, Lim ST, Ong CJ, Ong CK, …

Super-enhancer-driven TOX2 Mediates Oncogenesis in Natural Killer/T Cell Lymphoma (Mol Cancer., Apr 2023) Read More »

Xu C, Huang KK, Law JH, Chua JS, Sheng T, Flores NM, Pizzi MP, Okabe A, Tan ALK, Zhu F, Kumar V, Lu X, Benitez AM, Lian BSX, Ma H, …

Comprehensive Molecular Phenotyping Of ARID1A-deficient Gastric Cancer Reveals Pervasive Epigenomic Reprogramming and Therapeutic Opportunities (Gut, Mar 2023) Read More »

A team of researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore, co-led by Professor Daniel G. Tenen and Associate Professor Polly Chen Leilei, has for …

Novel Role of RNA Editing by ADAR2 in Core Binding Factor Acute Myelogenous Leukemias Read More »

Wee-Joo Chng 1 2, Sagar Lonial 3, Gareth J Morgan 4, Shinsuke Iida 5, Philippe Moreau 6, Shaji K Kumar 7, Philip Twumasi-Ankrah 8, Miguel Villarreal 8, Ajeeta B Dash 8, Alexander Vorog 8, Xiaoquan Zhang 8, Kaveri Suryanarayan 8, Richard Labotka 8, Meletios A Dimopoulos 9, S Vincent Rajkumar 7 Affiliations 1Department of Hematology-Oncology, National University Cancer Institute, Singapore, …

[Meta-Analysis] A Pooled Analysis of Outcomes According to Cytogenetic Abnormalities in Patients Receiving Ixazomib- vs Placebo-based Therapy for Multiple Myeloma (Blood Cancer J., Jan 23) Read More »

Win Lwin Thuya 1, Li Ren Kong 1 2 3, Nicholas L Syn 1 4, Ling-Wen Ding 1 5, Esther Sok Hwee Cheow 1, Regina Tong Xin Wong 1, Tingting Wang 1, Robby Miguel Wen-Jing Goh 1, Hongyan Song 1, Migara K Jayasinghe 2, Minh Tn Le 2 3, Jian Cheng Hu 3, Wei-Peng Yong 1 3 6, Soo-Chin Lee 1 3 6, Andrea Li-Ann Wong 1 3 6, Gautam Sethi 2 3, Huynh …

[Meta-Analysis] FAM3C in Circulating Tumor-derived Extracellular Vesicles Promotes Non-small Cell Lung Cancer Growth in Secondary Sites (Theranostics, Jan 23) Read More »

Robin Pearce 1, Xiaoqiang Huang 1, Gilbert S Omenn 1 2 3 4, Yang Zhang 1 5 6 7 Affiliations 1Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109. 2Department of Internal Medicine, University of Michigan, Ann Arbor, MI …

De Novo Protein Fold Design Through Sequence-independent Fragment Assembly Simulations (Proc. Natl. Acad. Sci. U S A, Jan 23) Read More »

Takayoshi Matsumura 1 2 3, Haruhito Totani 4, Yoshitaka Gunji 5, Masahiro Fukuda 6 7, Rui Yokomori 4, Jianwen Deng 4, Malini Rethnam 4, Chong Yang 4, Tze King Tan 4, Tadayoshi Karasawa 5, Kazuomi Kario 8, Masafumi Takahashi 5, Motomi Osato 4, Takaomi Sanda 4 9, Toshio Suda 10 11 12 Affiliations 1Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore. csitkm@nus.edu.sg. …

A Myb Enhancer-guided Analysis of Basophil and Mast Cell Differentiation (Nat Commun, Nov 22) Read More »