Job Description

We are seeking a highly motivated candidate for a research assistant position available in the Kappei Lab at the Cancer Science Institute of Singapore. Our team addresses research questions on how telomere-driven genomic instability contributes to carcinogenesis with quantitative mass spectrometry, cell biological and genetic approaches. Specifically, the successful candidate will be actively involved in a project investigating telomere-binding proteins in sarcoma. This project will span a variety of experimental approaches, e.g. gene editing of cancer cell lines, expression analysis of mRNA and protein as well as various mass spectrometry-based approaches to study DNA-protein and protein-protein interactions. Overall, the research assistant will support the research team in terms of research, laboratory and administrative needs.

Requirements

• Degree in life sciences or equivalent; fresh graduates are welcome to apply
• Excellent communication skills and good team spirit
• Fluent in spoken and written English
• Outstanding organizational skills

Practical experience with gene editing, cell and molecular biology techniques are an added advantage.

Applications should include in a single PDF a 1-page cover letter, curriculum vitae, certificates of qualifications and the names and contact information of at least 2 professional references. Please send applications with the reference “Kappei Lab RA 2025” to:

Dr. Dennis Kappei
Principal Investigator
CSI Singapore
Email: dennis.kappei[at]nus.edu.sg

Apply here.

Job Description

A Research Assistant position is required for Stephen Chong and Kong Li Ren’s team, which studies drug resistance mechanisms and molecular biology in cancers. This job recruitment is required to assist in managing on-going research projects. This job recruitment will provide much needed support to ensure the research group’s on-going projects will move forward more efficiently

Duties & Responsibilities

• Able to perform wet lab experiments independently with initial guidance
• Able to handle basic molecular techniques such as cell culture, western blotting and RT-PCR.
• Design and set up experimental workflow, reagents and tools
• Analyze, record and present data from assigned experiments
• Able to assist in ad hoc duties in the lab, which include supervising undergraduate students and handling administrative work

Qualifications

• Bachelor’s or Master’s degree in molecular biology, cancer biology, or related field
• Experience in running projects independently is preferred.
• Knowledge in cell culture and basic molecular biology techniques (western blotting, RT-PCR and flow cytometry)
• To be a team player with the ability to work collaboratively with other members of the lab.
• Ability to communicate fluently in written and spoken English

Apply here.

Job Description

To provide research support in applying deep learning and computational approaches to biological problems, specifically focusing on protein and RNA structure prediction/design and molecular interactions. The role will contribute to advancing our understanding of cancer biology through AI-driven analysis and modelling.

Duties & Responsibilities
•    Develop and implement deep learning models for modelling complex structures, using modern AI frameworks and computational tools
•    Process and analyse large-scale biological datasets, including molecular structure data
•    Collaborate with team members on various computational biology projects

Qualifications

• Bachelor's or Master's degree in Computer Science, Bioinformatics, Physics, Applied Mathematics, or related field
• Programming skills in Python and experience with deep learning frameworks (PyTorch)
• Knowledge of computational biology concepts and molecular structure analysis

Apply here.

Job Description

Job Purpose
The mission of the  Cancer Science Institute (National University of Singapore) is to better understand the causes of human cancer across Asia and thereby improve its detection, treatment, and prevention. Our outstanding researchers and exceptional facilities create an energetic environment for ground-breaking science and world-class training.

A Research Assistant position is available immediately in the Yvonne Tay team which studies RNA biology in cancers. You may refer to https://csi.nus.edu.sg/researcher/yvonne-tay/ for more information.

Interested applicants should include the following documents in the job application
1.    Curriculum Vitae (CV)
2.    Summary of past research experience
3.    Description of long-term plans
4.    3 referees including their name, contact information (email) and relationship to applicant

Duties & Responsibilities
Research:
•    Carry out assigned experiments under initial guidance and then independently
•    Organize, preserve, and present the results of the experiments in a logical manner
•    Record all assigned experiments and results properly and systematically
•    Analyse data and design subsequent experimental workflow
•    Assist in supervising, training and guiding attachment/undergraduate students as required

Administrative duties:
•    Assist with lab housekeeping and administrative duties as needed
•    Ensure that standard operating procedures and safety regulations are followed

Qualifications

•    Bachelor’s or Master’s degree in molecular biology, cancer biology, bioinformatics, computational biology, computer science, or related field
•    Interest in pursuing a research career in studying RNA biology in cancer
•    To be a team player with the ability to work collaboratively with other members of the lab.
•    Experience in running projects independently is preferred.
•    Experience in laboratory management is preferred but not essential.
•    Ability to communicate fluently in written and spoken English
•    Knowledge in cell culture and basic molecular biology techniques (western blotting/ RT-PCR etc)
•    Proficiency/ expertise in data analysis (R or equivalent)

Apply here.

Job Description

The Experimental Therapeutics Program seeks a Research Pathologist specializing in solid tumors, particularly breast cancer and nasopharyngeal cancer. The role involves providing pathology-related expertise to support translational research initiatives. This role is an exciting opportunity for a skilled pathologist to contribute to cutting-edge translational research in oncology, enhancing therapeutic strategies for solid tumors through rigorous pathological analysis and collaboration.

The selected candidate will be supporting Prof Lee Soo Chin, more information about her research available at https://csi.nus.edu.sg/researcher/soo-chin-lee/

Key Responsibilities:

1. Research Support:
   • Analyze morphological features of clinical samples for research purposes.
   • Score histological stains, including Immunohistochemistry (IHC), In Situ Hybridization (ISH), and Fluorescence In Situ Hybridization (FISH), in various research projects.
   • Manage and provide pathology-related technologies:
     • Develop and optimize immunohistochemistry assays.
     • Handle tissue arrays.
     • Conduct laser microdissection.
     • Utilize autostainer technology.
     • Operate slide imaging systems.
     • Use advanced microscopy systems.
2. Supervision and Teaching:
   • Supervise and mentor junior staff members.
   • Lead pathology-based projects.
3. Manuscripts and Grants:
   • Assist in the compilation of manuscripts and grant applications.

Qualifications

• Educational Background:
  • MBBS or MD degree is mandatory.
• Experience and Skills:
  • Preference for candidates with several years of experience as a diagnostic histopathologist or surgical pathologist.
  • Hands-on experience in one or more of the following:
    • Immunohistochemistry
    • Laser capture microdissection
    • Construction of tissue microarrays
    • Diagnostic molecular biology techniques and technologies
  • Profound understanding of pathological processes at the tissue level.
  • Ability to work independently.
  • Proficiency in written and spoken English.
  • Excellent writing and reporting abilities.
  • Strong communication skills and a collaborative attitude towards working in a multidisciplinary environment.

Additional Considerations:

• The ideal candidate will demonstrate a strong background in the morphological analysis of tumors, with an ability to integrate pathology insights into broader research contexts.
• Proven track record of developing and implementing novel pathology techniques and contributing to multidisciplinary research teams.

Apply here.

Please also email Kelly Ong your resume after submitting online: kellyong@nus.edu.sg.

Job Description

Highly motivated and creative postdoctoral candidates are sought to work at the Yang Zhang Lab, Cancer Science Institute of Singapore, School of Computing, and Yong Loo Lin School of Medicine, at National University of Singapore.

Candidates, who are interested in artificial intelligence (AI) and deep machine learning, protein and RNA structural prediction, protein and peptide design and engineering, and/or protein-ligand docking and drug screening, are encouraged to apply. We are particularly interested in the development of new AI-based approaches to cancer therapeutics, including antibody design and discovery, T cell receptor T cell therapy (TCR-T), and peptide-drug conjugate (PDC) cancer therapy. Focus of our laboratory is more on new and creative algorithm/platform developments rather than application of existing programs. Therefore, skills in computational coding and creativity in scientific method design, together with interest in computational cancer medicine, are critical to the position. Previous experience in machine learning will be a plus. More details on our projects can be found at https://zhanggroup.org.

To apply, please send your CV, a brief description of your research interest and plan, and contact information of three professional referees to Prof Yang Zhang (Email: zhang@nus.edu.sg).

Apply here.

The position of Postdoctoral Fellow - with an emphasis on computational cancer genomics - is immediately available at the Cancer Science Institute of Singapore (a part of National University of Singapore). The Postdoctoral Fellow will work with the laboratories of Professor Ashok Venkitaraman, on a project studying the evolution of cancer genomes during early steps in carcinogenesis, with the long-term aim to develop better methods for early intervention.

This is an exciting opportunity to deploy expertise in computational biology in an active multidisciplinary environment, working closely with experimental cancer biologists to address major scientific problems.

The Postdoctoral Fellow will apply existing analytic pipelines and devise new algorithms to explore data derived from multiple DNA sequencing technologies (e.g., Illumina & Nanopore) to resolve cancer genome evolution at the clonal level. S/he will also analyse complementary data from other technologies, ranging from single-cell RNAseq to chromatin immunoprecipitation to chromatin accessibility (ATAC-seq), using a variety of novel cellular models established in Professor Venkitaraman’s laboratory. Experimental findings will be explored and validated using clinical genomic datasets.

Please refer to https://csi.nus.edu.sg/researcher/ashok-venkitaraman/ for more information on Professor Ashok Venkitaraman’s research

Interested applicants should include the following documents in the job application

1. Curriculum Vitae (CV)
2. Summary of past research experience
3. Description of long-term plans
4. At least 3 referees including their name, contact information (email) and relationship to applicant

Qualifications

The applicant for this position should possess a PhD in Human genetics, Genomics, Bioinformatics, Computer science, or related fields, with a strong track record of achievement exemplified by publications, is important, as is the required expertise in computational biology listed below. Experience in the methods to be used in the project is desirable.

• Firm understanding of the principles of clonal evolution
• Experience analyzing DNA sequencing data
• Strong Python and/or R programming skills
• Proficient with standard statistical analyses
• Strong publication record
• Excellent written and spoken English

PREFERENCES

• Experience using Amazon Web Services
• Proficiency with Unix-based systems
• Experience with collaborative software development via github/gitlab

Apply here.

The position of Postdoctoral Fellow - with an emphasis on computational cancer genomics - is immediately available at the Cancer Science Institute of Singapore (a part of National University of Singapore). The Postdoctoral Fellow will work with the laboratories of Professor Ashok Venkitaraman, on a project studying the evolution of cancer genomes during early steps in carcinogenesis, with the long-term aim to develop better methods for early intervention.

This is an exciting opportunity to deploy expertise in computational biology in an active multidisciplinary environment, working closely with experimental cancer biologists to address major scientific problems.

The Postdoctoral Fellow will apply existing analytic pipelines and devise new algorithms to explore data derived from multiple DNA sequencing technologies (e.g., Illumina & Nanopore) to resolve cancer genome evolution at the clonal level. S/he will also analyse complementary data from other technologies, ranging from single-cell RNAseq to chromatin immunoprecipitation to chromatin accessibility (ATAC-seq), using a variety of novel cellular models established in Professor Venkitaraman’s laboratory. Experimental findings will be explored and validated using clinical genomic datasets.

Please refer to https://csi.nus.edu.sg/researcher/ashok-venkitaraman/ for more information on Professor Ashok Venkitaraman’s research

Interested applicants should include the following documents in the job application

1. Curriculum Vitae (CV)
2. Summary of past research experience
3. Description of long-term plans
4. At least 3 referees including their name, contact information (email) and relationship to applicant

Duties And Responsibilities

The applicant for this position should possess a PhD in Human genetics, Genomics, Bioinformatics, Computer science, or related fields, with a strong track record of achievement exemplified by publications, is important, as is the required expertise in computational biology listed below. Experience in the methods to be used in the project is desirable.

• Firm understanding of the principles of clonal evolution
• Experience analyzing DNA sequencing data
• Strong Python and/or R programming skills
• Proficient with standard statistical analyses
• Strong publication record
• Excellent written and spoken English

PREFERENCES

• Experience using Amazon Web Services
• Proficiency with Unix-based systems
• Experience with collaborative software development via github/gitlab

Apply here.

Job Description

Are you a biomedical researcher motivated to pursue an outstanding career in cancer research with a focus on structural biology?

Cancer will affect more than 1 in 3 Singaporeans. At the Cancer Science Institute (CSI), our mission is to be at the global forefront of research to overcome this scourge. Our innovative international faculty, cutting-edge facilities, supportive working environment and competitive package together enable each of our staff to realize their maximum potential.

We now seek a Research Scientist/ Senior Research Scientist to join the team of Prof. Ashok Venkitaraman. This is an exciting opportunity to work closely with a world-leading cancer researcher to undertake pioneering research on the role of genome instability in human carcinogenesis (eg., see Venkitaraman Science (2014) PMID:24675954 and Venkitaraman DNA Repair (2019) PMID:31337537).

Please refer to https://csi.nus.edu.sg/researcher/ashok-venkitaraman/ for more information on Professor Ashok Venkitaraman’s research

For this position, we would require a post-doctoral fellow to engage in designing and running of multiple CRISPR genome screens, to interrogate and identify genes that are responsible for a host of different genome instability phenomenon uncovered in our lab in human carcinogenesis

We are looking for highly motivated individuals with the ability to work in a team environment. Genuine enthusiasm for science, willingness to think beyond established concepts and to try and learn new experimental and analysis tools.

Duties And Responsibilities
Laboratory skills:
•    Required experience with CRISPR gene editing and screens
•    Required experience with mammalian cell culture
•    Required experience with molecular cloning and biochemical analyses (qPCR, Western, co-IP, etc.)
•    Good to have experience in high-throughput sequencing and data analysis (RNAseq etc.)

Qualifications

•    PhD in biology or related fields
•    Strong track record of research achievement evidenced by high-quality publications in a relevant field
•    High-level experience in hands-on use of a wide range of relevant research methods
•    Skills in working independently and creatively to solve experimental problems
•    Effective communication and presentation skills, with experience in communicating scientific work including scientific papers, presentations and reports.

Apply here.

Job Description

The Cancer Science Institute of Singapore (CSI Singapore) Postdoctoral Fellowship seeks outstanding early-stage postdoctoral fellows who are interested to develop their career as independent, tenure-track faculty. The awardees will be hosted within established research labs at CSI Singapore to develop their independent research programs. They will receive a competitive base salary of up to SGD$93,000 per year (not including benefits such as CPF, bonus, medical, insurance) with an annual research grant of up to SGD$25,000 per year and equipment grant of SGD$5,000. Access to state-of-the-art core facilities will be provided. The fellowship funding period is up to three years.

Qualifications

• Open to all nationalities.
• Soon-to-be PhD graduates or have graduated within four years from their respective PhD programs at the time of application. Exceptions may be considered on a case-by-case basis.
• Received at least two years of graduate training outside of Singapore (either overseas PhD training or postdoctoral training)
• Work in any discipline of cancer research
• Excellent track record of research accomplishments
• Keen to embark on exciting and innovative projects in experimental and/or bioinformatics laboratories
• Aspire to be leaders in biomedical research
• Be available to take up position within 6 months of notice of award

Application

Bi-annual review with two submission deadlines – 30th April and 31st October

Please consolidate the following documents as one PDF document and attach it in your application.

1. Cover letter,
2. Curriculum Vitae (CV) including full publication list,
3. Research Proposal (two pages, excluding references) summarising the background, significance, aims and methods of the proposed research,
4. Personal Statement (one page) about research interest, career aspirations and motivations for applying for Fellowship, and
5. Names and contact information of 2 – 3 references (including PhD supervisor)

Apply via: https://careers.nus.edu.sg/job-invite/27266/