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May 5, 2022
CSI Principal Investigator and Senior Research Scientist Receive Awards at the Asian Fund for Cancer Research’s (AFCR) 2021 BRACE Award Venture Competition
Congratulations to A/Prof. Edward Kai-Hua Chow and Dr. Bee Hui Liu, who have recently won awards at the Asian Fund for Cancer Research’s (AFCR) 2021 BRACE Award Venture Competition, a...
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May 5, 2022
Multilayered Control of Splicing Regulatory Networks by DAP3 Leads to Widespread Alternative Splicing Changes in Cancer. (Nat Commun, Apr 22)
Jian Han 1, Omer An 2, Xi Ren 2, Yangyang Song 2, Sze Jing Tang 2, Haoqing Shen 2, Xinyu Ke 2, Vanessa Hui En Ng 2, Daryl Jin Tai Tay 2, Hui Qing Tan 3, Dennis Kappei 2 4 5, Henry Yang 2, Leilei Chen 6 7 8 Affiliations 1Cancer Science Institute of Singapore, National University of Singapore,...
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Press Release

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qChIP-MS reveals the local chromatin composition by label-free quantitative proteomics

Researchers led by Principal Investigator, Assistant Professor Dennis Kappei, have developed a new method that allows scientists to better understand how DNA activity is organised and regulated inside our cells. […]

An Analytic Framework Characterizes the Biological Processes That Shape Copy Number–Based Genome Instability Patterns in Breast Cancer

 A study led by Principal Investigator, Dr. Jason Pitt, has identified eight new “signatures” of DNA patterns (gains and/or losses) in breast cancer. By analysing nearly 2,800 genomes, the team […]

A Paired Sequence Language Model for Protein-Protein Interaction Modeling

Researchers led by Senior Principal Investigator, Professor Zhang Yang, have developed a new artificial intelligence (AI) model that can more accurately predict how proteins interact with one another—an advance that […]

Learned Conformational Space and Pharmacophore into Molecular Foundational Model

A key challenge in AI-driven drug discovery is moving beyond molecular analysis to enable chemically meaningful molecular design. In a newly published study in Advanced Science, researchers led by Senior […]

Pembrolizumab Plus Lenvatinib in Recurrent Gynaecological Clear Cell Carcinoma (LARA): A Multicentre, Single-Arm, Phase 2 Trial (The LANCET Oncology, Feb 2026)

A multinational study led by Principal Investigator A/Prof. David Tan and collaborators from Singapore and South Korea has demonstrated encouraging results for patients with recurrent clear cell ovarian and endometrial […]

Induction of a metabolic switch from glucose to ketone metabolism programs ketogenic diet-induced therapeutic vulnerability in lung cancer (Cell Metabolism Nov 2025)

Authors Zhengwei Wu , Zhenxun Wang , Seow Qi Ng , Jessica Alice Lidster , Paul Schwerd-Kleine , Zi Jin Cheryl Phua , Kai Lay Esther Peh , Yin Ying […]

Pragmatic Interventions to Boost Surveillance Mammogram Uptake Among an Overdue Population A Randomized Clinical Trial (JAMA Internal Medicine, Nov 2025)

Authors Soo-Chin Lee, Sasidharan Swarnalatha Lucky, Junxian Zhu, Samuel Ow, Lukas Loh, Jun Hui Tan, Siew Eng Lim, Zarinah Hairom, Shivan Mehta 6, Bee-Choo Tai, Boon-Cher Goh Abstract Led by […]

Aggressive B cell lymphomas retain ATR-dependent determinants of T cell exclusion from the germinal center dark zone (JCI, July 2025)

Authors: Valeria Cancila, Giorgio Bertolazzi, Allison S.Y. Chan, Giovanni Medico, Giulia Bastianello, Gaia Morello, Daniel Paysan, Clemence Lai, Liang Hong, Girija Shenoy, Patrick W. Jaynes, Giovanna Schiavoni, Fabrizio Mattei, Silvia […]

Prospective Clinical Validation of a Combinatorial Functional Precision Medicine Platform in Relapsed/Refractory Non-Hodgkin’s Lymphoma (JCO Precision Oncology, September 2025)

Treating patients whose non-Hodgkin’s lymphoma (NHL) has come back or stopped responding to therapy remains very difficult. Many eventually run out of standard treatment options. A team led by Dr. […]

🚨 New Milestone in Cancer Research and Precision Medicine 🚨

CSI Singapore and Next&Bio Launch Joint Organoid Research Laboratory at NUS We are excited to announce the launch of a joint organoid research laboratory by Next&Bio and the Cancer Science […]

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