1.       SY Toh, HS Leong, FT Chong, DM Rodrigues-Junior, XL Kwang, DPX Lau, PH Lee, AL Vettore, BT Teh, DSW Tan, NG Iyer.  Therapeutic application of extracellular vesicular EGFR isoform D as a co-drug strategy to target squamous cell cancers with tyrosine kinase inhibitors.  Developmental Cell, 59(16): 2189-2202 (2024)

 

2.       C Adine, K Fernando, NCW Ho, HS Quah, SSW Ho, KWW Teng, C Arcinas, L Li, K Ha, JWL Chew, C Wang, NSH Too, H Bhuvaneswari, R Nagadia, JPS Yeong, NG Iyer, ELS Fong.  Bioengineered hydrogels enhance ex vivo preservation of patient-derived tumor explants for drug evaluation.  Biomaterials, 305: 122460 (2024)

 

3.       HS Quah, EY Cao, L Suteja, CH Li, HS Leong, FT Chong, S Gupta, C Arcinas, JF Ouyang, V Ang, T Celhar, Y Zhao, HC Tay, J Chan, T Takahashi, DSW Tan, SK Biswas, OJL Rackham, NG Iyer.  Single cell analysis in head and neck cancer reveals potential immune evasion mechanisms during early metastasis.  Nature Communications, 14(1): 1680 (2023)

 

4.       DWT Lim, HF Kao, L Suteja, CH Li, HS Quah, DSW Tan, SH Tan, EH Tan, WL Tan, JN Lee, FYT Wee, A Jain, BC Goh, MLK Chua, BC Liao, QS Ng, RL Hong, MK Ang, JPS Yeong, NG Iyer.  Clinical efficacy and biomarker analysis of dual PD-1/CTLA-4 blockade in recurrent/metastatic EBV-associated nasopharyngeal carcinoma. Nature Communications, 14(1): 2781 (2023)

 

5.       Y Sun, S Selvarajan, Z Zang, W Liu, Y Zhu, H Zhang, W Chen, H Chen, L Li, X Cai, H Gao, Z Wu, L Chen, X Teng, Y Zhao, X Teng, S Mantoo, TKH Lim, B Hariraman, S Yeow, SMFS Abdillah, SS Lee, G Ruan, Q Zhang, T Zhu, W Wang, G Wang, J Xiao, Y He, Z Wang, W Sun, Y Qin, Q Xiao, X Zheng, L Wang, X Zheng, K Xu, Y Shao, K Liu, S Zheng, R Aebersold, Z Li, OL Kon, NG Iyer, T Guo. Artificial intelligence defines protein-based classification of thyroid nodules. Cell Discovery, 8(1): 85 (2022)

 

6.       A Sharma, EY Cao, HS Leong, V Kumar, N Ramakrishnan, AML Wong, M Hakimullah, X Zhang, HM Teo, FT Chong, S Chia, MT Thangavelu, XL Kwang, DSW Tan, R Gupta, JR Clark, G Periyasamy, NG Iyer, R DasGupta. Longitudinal single-cell RNA sequencing of patient-derived primary cells reveals drug-induced infidelity in stem-cell hierarchy. Nature Communications, 9: 4931 (2018)

 

 

7.       Rasheed SAK, Leong HS, Lakshmanan M, Raju A,Dadlani D, Chong FT, Shannon NB, Rajarethinam R, Skanthakumar T, Tan EY, Hwang JSG, Lim KH, Tan DSW, Ceppi P, Wang M, Tergonkar V, Casey PJ, Iyer NG. GNA13 expression promotes drug resistance and tumor-initiating phenotypes in squamous cell cancers. Oncogene, 37(10): 1340-1353 (2018)

 

8.       Chia S, Low JL, Zhang X, Kwang XL, Chong FT, Sharma A, Bertrand D, Toh SY, Leong HS, Thangavelu MT, Hwang JSG, Lim KH, Skanthakumar T, Tan HK, Su Y, Choo SH, Hentze H, Tan IBH, Lezhava A, Tan P, Tan DSW, Periyasamy G, Koh JLY, Iyer NG, DasGupta R. Phenotype-driven precision oncology as a guide for clinical decisions one patient at a time. Nature Communications, 8(1): 435 (2017)

 

 

9.       Tan DSW, Chong FT, Leong HS, Toh SY, Lau DP, Kwang XL, Zhang XQ, Sundaram GM, Tan GS, Chang MM, Chua BT, Lim WT, Tan EH, Ang MK, Lim TKH, Sampath P, Chowbay B, Skanderup AJ, DasGupta R, Iyer NG.  Long noncoding RNA EGFR-AS1 mediates epidermal growth factor receptor addiction and modulates treatment response in squamous cell carcinoma. Nature Medicine, 23(10): 1167-1175 (2017)

 

10.   Vettore AL, Ramnarayanan K, Poore G, Lim K, Ong CK, Huang KK, Leong HS, Chong FT, Lim TKH, Lim WK, Cuctcutche I, Mcpherson JR, Suzuki Y, Zhang, S, Skanthakumar T, Wang W, Tan DSW, Cho BC, Teh BT, Rozen S, Tan P, Iyer NG. Mutational landscapes of tongue carcinoma reveal recurrent mutations in genes of therapeutic and prognostic relevance. Genome Medicine, 7(1): 98 (2015)
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