BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//NUS CSI - ECPv6.11.0.1//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-WR-CALNAME:NUS CSI
X-ORIGINAL-URL:https://csi.nus.edu.sg
X-WR-CALDESC:Events for NUS CSI
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:UTC
BEGIN:STANDARD
TZOFFSETFROM:+0000
TZOFFSETTO:+0000
TZNAME:UTC
DTSTART:20190101T000000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=UTC:20190705T050000
DTEND;TZID=UTC:20190705T060000
DTSTAMP:20260408T062515
CREATED:20230120T001553Z
LAST-MODIFIED:20230130T014739Z
UID:47841-1562302800-1562306400@csi.nus.edu.sg
SUMMARY:CSI Research Meeting - 5 Jul
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/csi-research-meeting-5-jul/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190709T090000
DTEND;TZID=UTC:20190709T100000
DTSTAMP:20260408T062515
CREATED:20230120T001814Z
LAST-MODIFIED:20230130T014633Z
UID:47878-1562662800-1562666400@csi.nus.edu.sg
SUMMARY:Joint SGCC-CSI Gastric Cancer Seminar - 9 July 2019
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/joint-sgcc-csi-gastric-cancer-seminar-9-july-2019/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190716T040000
DTEND;TZID=UTC:20190716T050000
DTSTAMP:20260408T062515
CREATED:20230120T001815Z
LAST-MODIFIED:20230130T014450Z
UID:47879-1563249600-1563253200@csi.nus.edu.sg
SUMMARY:MSC-Olink Joint Workshop "Olink to Accelerate Proteomic Discoveries for Precision Medicine"
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/msc-olink-joint-workshop-olink-to-accelerate-proteomic-discoveries-for-precision-medicine/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190719T040000
DTEND;TZID=UTC:20190719T050000
DTSTAMP:20260408T062515
CREATED:20230120T002013Z
LAST-MODIFIED:20230130T014359Z
UID:47880-1563508800-1563512400@csi.nus.edu.sg
SUMMARY:Research Seminar by Prof Nan-Shan Chang on "Tumor Suppressor WWOX is a Risk Factor for Alzheimer's Disease"
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/research-seminar-by-prof-nan-shan-chang-on-tumor-suppressor-wwox-is-a-risk-factor-for-alzheimers-disease/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190719T050000
DTEND;TZID=UTC:20190719T060000
DTSTAMP:20260408T062515
CREATED:20230120T001554Z
LAST-MODIFIED:20230130T014216Z
UID:47842-1563512400-1563516000@csi.nus.edu.sg
SUMMARY:CSI Research Meeting - 19 Jul
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/csi-research-meeting-19-jul/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190725T080000
DTEND;TZID=UTC:20190725T093000
DTSTAMP:20260408T062515
CREATED:20230120T002523Z
LAST-MODIFIED:20230120T002523Z
UID:47923-1564041600-1564047000@csi.nus.edu.sg
SUMMARY:Regular Haematology-Oncology Interest Group Combine Meeting - 25 Jul
DESCRIPTION:1st Speaker –\n“Hematopoietic Stem Cell Integrity is Dependent on Chromosome Structure Maintained by ZNF143” \n–       Dr. Zhou Qiling from Prof Daniel Tenen’s lab\n\n\n2nd Speaker –\n“Successful Application of the Quadratic Phenotypic Optimisation Platform in a case of Refractory T cell Lymphoma” \n–       Dr Sanjay\, Consultant from Department of Haematology-Oncology\n\n\n\n 
URL:https://csi.nus.edu.sg/event/regular-haematology-oncology-interest-group-combine-meeting-25-jul/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190729T030000
DTEND;TZID=UTC:20190729T040000
DTSTAMP:20260408T062515
CREATED:20230120T002014Z
LAST-MODIFIED:20230120T002014Z
UID:47881-1564369200-1564372800@csi.nus.edu.sg
SUMMARY:RNA Biology Centre Meeting - 29 July
DESCRIPTION:By Invitation Only\nDate: 29 July 2019\, Monday\nTime: 11am\nVenue: MD6\, Level 12 Conference Room (#12-02N) \n  \nScientific Presentation:\nSpeaker: Touati Benoukraf\nTitle:   Building an Asian AML genome reference to improve RNA analysis  \n  \nAbstract:\n \nA key step in RNAseq analysis is mapping sequenced reads to a genome reference. However\, for certain diseases such as Acute Myeloid Leukemia\, the human genome reference can be far from the actual patients’ genome of affected cells\, due to the numerous structural variants (translocations\, insertions\, duplications\, and deletions). More distant is the actual genome from the reference genome\, less specific will be the mapping\, and consequently\, less accurate will be the final analyses and interpretations. The recent advent of third-generation sequencing (3GS) technologies brings promise for better characterization of genomic aberrations by virtue of having longer reads. Although current applications of 3GS are restricted by their high sequencing error rates and low sequencing throughput\, we were able to overcome these limitations\, by developing an algorithm that employs split-reads and hard-clipped reads for SV detection\, combined to a neural network classifier for true SV enrichment on low-depth 3GS datasets generated by the Oxford Nanopore technology. In simulated data\, we demonstrated that our method provides the highest SV detection accuracy (F1 score = 0.91) amongst other long-read SV callers using 12 gigabases (4X) of sequencing data. In patient samples\, besides the detection of genomic aberrations\, our method also uncovered many normal alternative sequences or alleles which were present in healthy individuals. The low sequencing depth requirements for our method enable the use of Nanopore sequencing for accurate SV characterization and understanding their effects on transcription regulation at a lower sequencing cost\, an approach compatible with clinical studies. \n 
URL:https://csi.nus.edu.sg/event/rna-biology-centre-meeting-29-july/
END:VEVENT
END:VCALENDAR