NUS CSI

CSI Seminar - Chew Guo Liang
2019-08-27 03:00 - 04:00 UTC

Joint SGCC-CSI Gastric Cancer Seminar - 3 Sep 2019
2019-09-03 09:00 - 10:00

RNA Club - 5 Sept
2019-09-05 03:00 - 04:00
Speaker: Dr Jonathan GÖKEVenue: NUS, MD6, Level 12 conference room
Time: 11 am
Title: Exploring the complexity of the transcriptome: from a Pan-Cancer analysis of alternative promoters to Nanopore direct RNA-Sequencing of full length RNAs
Host: Dr Polly Chen

Regular Haematology-Oncology Interest Group Combine Meeting - 5 Sep
2019-09-05 08:00 - 09:30
1st Speaker –
“DNA Damage Induces Type I Interferon Related Responses in Diffuse B Cell Lymphoma”
– Dr. Patrick Jayne William from Dr Anand Jeyasekharan’s lab

2nd Speaker –
“Interesting Cases Encountered from our Clinical Myeloid Neoplasm NGS Service’”
– Dr Ben Yan, Consultant from Department of Haematology-Oncology

RNA Biology Centre Meeting – 16 Sep
2019-09-16 03:00 - 04:00
Meeting Agenda:

Scientific work presentation:
Speaker: Jobichen Chacko
Talk title: Structural and functional studies of DNMT1 to understand its role in DNA methylation

Abstract
DNA methylation is an epigenetic mechanism implicated in transcriptional regulation, genomic imprinting and silencing of repetitive DNA elements. The addition of methyl groups is controlled at several different levels in cells and is carried out by a family of enzymes called DNA methyltransferases (DNMTs). DNMT1 mediates the maintenance of established patterns of DNA methylation. DNMT1 is a multimodular protein composed of a replication foci-targeting domain (RFD), a DNA-binding CXXC domain, a pair of bromo-adjacent homology (BAH) domains and a C-terminal catalytic domain. The structure of DNMT1-DNA complex is already reported and it reveals the binding regions of DNMT1 with DNA. Recent studies have shown that various RNA fragments also bind to DNMT1 to prevent genomic methylation. The pull-down assay using the various domains of DNMT1 showed that the C-terminal region is involved in binding to RNA. We have expressed and purified various fragments from human-DNMT1 in order to gain further insights by elucidating the structure of DNMT1-RNA complex.

NanoString Summit 2019-5th User Group Meeting Singapore
2019-09-17 01:30 - 08:00

CSI Distinguished Speakers’ Series – Iannis Aifantis
2019-09-17 02:00 - 03:00

Fearless Science Symposium
2019-09-18 00:00 - 09:00

CSI Seminar - Susumu Kobayashi
2019-09-19 03:00 - 04:00

CSI Research Meeting - 27 Sept
2019-09-27 05:00 - 06:00

CSI Seminar - Francesco Ferrari
2019-10-01 07:00 - 08:00

RNA Biology Symposium 2019
2019-10-03 01:00 - 2019-10-04 09:00

CSI Graduate Recruitment
2019-10-08 04:00 - 06:00

CSI Research Meeting - 11 Oct
2019-10-11 03:00 - 04:00

CSI Seminar - Lucy A. Godley
2019-10-14 07:00 - 08:00

RNA Club - 29 Oct
2019-10-29 03:00 - 04:00

Miltenyi Biotec - MacsQuant X Overview Demonstration
2019-10-30 03:30 - 04:30

Regular Haematology-Oncology Interest Group Combine Meeting - 31 Oct
2019-10-31 08:00 - 09:30
1st Speaker –
“Feed-forward Regulatory Loop Driven by IRF4 and NF-?B in Adult T-cell Leukemia/Lymphoma”
– Dr. Regina Wong from Dr Takaomi Sanda’s Lab

2nd Speaker –
“Characterization and Risk Stratification of Genetic Subtypes of Childhood B-Lymphoblastic Leukemia Classified by RNA Sequencing”
– Dr Li Zhenhua from Prof Allen Yeoh’s Lab

Frontiers in Cancer Science 2019
2019-11-04 00:00 - 2019-11-06 09:00

Bioinformatics Workshop - 11 Nov
2019-11-11 01:30 - 09:00

Seminar by Dr Chen Jin
2019-11-26 02:00 - 03:00

Regular Haematology-Oncology Interest Group Combine Meeting - 28 Nov
2019-11-28 08:00 - 09:30
1st Speaker –
“Mitochondria Transfer in Erythroblastic Island Niche”
– Dr. Yang Chong from Prof Toshio Suda’s Lab

2nd Speaker –
“Analysis of MYC, BCL2 and BCL6 at Single Cell Resolution Identifies a Prognostically Relevant Cell Population in DLBCL”
– Michal Marek Hoppe from Dr Anand D Jeyasekharan’s Lab

NUS Physiology Research Seminar - Boris Turk
2019-12-06 02:00 - 03:00

CSI Seminar - Edwin Antony
2019-12-13 03:00 - 04:00

RNA Club – 7 Jan
2020-01-07 03:00 - 04:00
Speaker: Dr Chun Kit KWOKVenue: NUS, MD6, Level 12 conference room
Time: 11 am
Title: Mapping and Targeting RNA G-Quadruplex Structures
Host: Dr Polly Chen

CSI Seminar - George A. Calin
2020-01-08 03:00 - 04:00

NUS Physiology Research Seminar - Michael Ristow
2020-01-09 04:00 - 05:00

CSI Research Meeting - 10 Jan
2020-01-10 05:00 - 06:00

CSI PhD Oral Defense – Michal Marek HOPPE
2020-01-14 01:30 - 03:00

CSI Seminar - Jean-Baptiste Vannier
2020-01-16 03:00 - 04:00
