BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//NUS CSI - ECPv6.11.0.1//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-WR-CALNAME:NUS CSI
X-ORIGINAL-URL:https://csi.nus.edu.sg
X-WR-CALDESC:Events for NUS CSI
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:UTC
BEGIN:STANDARD
TZOFFSETFROM:+0000
TZOFFSETTO:+0000
TZNAME:UTC
DTSTART:20190101T000000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=UTC:20190118T020000
DTEND;TZID=UTC:20190118T030000
DTSTAMP:20260423T142327
CREATED:20230120T001510Z
LAST-MODIFIED:20230130T024440Z
UID:47829-1547776800-1547780400@csi.nus.edu.sg
SUMMARY:CSI Seminar - Charles David
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/csi-seminar-charles-david/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190118T063000
DTEND;TZID=UTC:20190118T073000
DTSTAMP:20260423T142327
CREATED:20230120T001508Z
LAST-MODIFIED:20230130T024132Z
UID:47826-1547793000-1547796600@csi.nus.edu.sg
SUMMARY:CSI Seminar - Chiang Cheng-Ming
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/csi-seminar-chiang-cheng-ming/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190121T063000
DTEND;TZID=UTC:20190121T073000
DTSTAMP:20260423T142327
CREATED:20230120T001706Z
LAST-MODIFIED:20230130T024112Z
UID:47858-1548052200-1548055800@csi.nus.edu.sg
SUMMARY:CSI Distinguished Speakers’ Series – Samuel Waxman
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/csi-distinguished-speakers-series-samuel-waxman/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190125T050000
DTEND;TZID=UTC:20190125T060000
DTSTAMP:20260423T142327
CREATED:20230119T230227Z
LAST-MODIFIED:20230130T024006Z
UID:47786-1548392400-1548396000@csi.nus.edu.sg
SUMMARY:CSI Research Meeting - 25 Jan
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/csi-research-meeting-25-jan/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190218T000000
DTEND;TZID=UTC:20190218T090000
DTSTAMP:20260423T142327
CREATED:20230120T001608Z
LAST-MODIFIED:20230130T023940Z
UID:47846-1550448000-1550480400@csi.nus.edu.sg
SUMMARY:CSI Distinguished Speakers’ Series – Reuben Harris
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/csi-distinguished-speakers-series-reuben-harris/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190221T080000
DTEND;TZID=UTC:20190221T093000
DTSTAMP:20260423T142327
CREATED:20230120T001720Z
LAST-MODIFIED:20230130T023921Z
UID:47861-1550736000-1550741400@csi.nus.edu.sg
SUMMARY:SRBA Meeting - 21 Feb
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/srba-meeting-21-feb-2/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190222T050000
DTEND;TZID=UTC:20190222T060000
DTSTAMP:20260423T142327
CREATED:20230119T230229Z
LAST-MODIFIED:20230130T023845Z
UID:47788-1550811600-1550815200@csi.nus.edu.sg
SUMMARY:CSI Research Meeting - 22 Feb
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/csi-research-meeting-22-feb/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190226T030000
DTEND;TZID=UTC:20190226T040000
DTSTAMP:20260423T142327
CREATED:20230120T001609Z
LAST-MODIFIED:20230120T001609Z
UID:47848-1551150000-1551153600@csi.nus.edu.sg
SUMMARY:RNA Biology Centre Meeting - 26 Feb
DESCRIPTION:Venue: Level 12 Conference Room\nTime: 11am \nScientific work presentation: \nSpeaker: Xin Yi LOH (Prof H. Phillip Koeffler’s group) \nTitle: ZFP36L1 suppresses hypoxia and cell cycle signaling \nAbstract: \nZFP36L1 is a tandem zinc-finger RNA binding protein (RBP) that recognizes conserved Adenylate-Uridylate-rich elements (AU-rich elements\, AREs) located in 3’untranslated regions (UTRs) mediating mRNAs decay process. Here\, we hypothesized that ZFP36L1 is a negative regulator of a post-transcriptional hub involving in mRNA half-life regulation of cancer-related transcripts. To identify the direct downstream targets of ZFP36L1\, a systematic screening using RNA pull-down and whole transcriptome sequencing of bladder cancer cells ± ZFP36L1 was performed. Analysis of in silico data revealed that ZFP36L1 is significantly mutated\, epigenetically silenced and downregulated in a variety of cancers. Forced expression of ZFP36L1 in cancer cells markedly reduced in vitro and in vivo cell proliferation; whereas silencing of ZFP36L1 enhanced tumor cells growth. We identified a network of 1\,410 targets\, which were bound by wildtype\, but not zinc finger mutant ZFP36L1. These targets included a number of key oncogenic transcripts\, such as HIF-1?\, CCND1 and E2F1. ZFP36L1 specifically bound to 3’UTRs of these targets for mRNA degradation\, thus suppressing their mRNA and protein expressions. Dual luciferase reporter assays and RNA Electro-Mobility Shift Assays (RNA-EMSA) showed that wildtype\, but not zinc finger mutant ZFP36L1\, bound to HIF-1? 3’UTR and mediated HIF-1? mRNA degradation. This eventually leads to reduced expressions of HIF-1? and its downstream targets in metabolism and angiogenesis. Collectively\, our findings shed light on the pathophysiology of bladder tumorigenesis and revealed an indispensable role of ZFP36L1 as a posttranscriptional safeguard against aberrant hypoxic signaling and abnormal cell cycle progression.
URL:https://csi.nus.edu.sg/event/rna-biology-centre-meeting-26-feb/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190227T063000
DTEND;TZID=UTC:20190227T073000
DTSTAMP:20260423T142327
CREATED:20230120T001454Z
LAST-MODIFIED:20230130T023824Z
UID:47823-1551249000-1551252600@csi.nus.edu.sg
SUMMARY:CSI Seminar - Peter Kharchenko
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/csi-seminar-peter-kharchenko/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190304T030000
DTEND;TZID=UTC:20190304T040000
DTSTAMP:20260423T142327
CREATED:20230120T001623Z
LAST-MODIFIED:20230130T023804Z
UID:47851-1551668400-1551672000@csi.nus.edu.sg
SUMMARY:RNA Club – 4 Mar
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/rna-club-4-mar/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190305T080000
DTEND;TZID=UTC:20190305T090000
DTSTAMP:20260423T142327
CREATED:20230120T001734Z
LAST-MODIFIED:20230130T023748Z
UID:47865-1551772800-1551776400@csi.nus.edu.sg
SUMMARY:CSI Seminar - Simón Méndez-Ferrer
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/csi-seminar-simon-mendez-ferrer/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190307T030000
DTEND;TZID=UTC:20190307T040000
DTSTAMP:20260423T142327
CREATED:20230120T001721Z
LAST-MODIFIED:20230130T023241Z
UID:47864-1551927600-1551931200@csi.nus.edu.sg
SUMMARY:[CANCELLED] CSI Seminar - Yan Chuan
DESCRIPTION:Due to unforeseen circumstances\, this seminar is CANCELLED.
URL:https://csi.nus.edu.sg/event/cancelled-csi-seminar-yan-chuan/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190308T050000
DTEND;TZID=UTC:20190308T060000
DTSTAMP:20260423T142327
CREATED:20230120T001525Z
LAST-MODIFIED:20230130T023215Z
UID:47833-1552021200-1552024800@csi.nus.edu.sg
SUMMARY:CSI Research Meeting - 8 March
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/csi-research-meeting-8-march/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190308T080000
DTEND;TZID=UTC:20190308T090000
DTSTAMP:20260423T142327
CREATED:20230120T001721Z
LAST-MODIFIED:20230130T022807Z
UID:47863-1552032000-1552035600@csi.nus.edu.sg
SUMMARY:CSI Seminar - Yoshiaki Kubota
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/csi-seminar-yoshiaki-kubota/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190321T030000
DTEND;TZID=UTC:20190321T040000
DTSTAMP:20260423T142327
CREATED:20230120T001719Z
LAST-MODIFIED:20230130T022701Z
UID:47860-1553137200-1553140800@csi.nus.edu.sg
SUMMARY:CSI Seminar - Ichiro Taniuchi
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/csi-seminar-ichiro-taniuchi-2/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190322T050000
DTEND;TZID=UTC:20190322T060000
DTSTAMP:20260423T142327
CREATED:20230120T001525Z
LAST-MODIFIED:20230130T022643Z
UID:47834-1553230800-1553234400@csi.nus.edu.sg
SUMMARY:CSI Research Meeting - 22 March
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/csi-research-meeting-22-march/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190405T050000
DTEND;TZID=UTC:20190405T060000
DTSTAMP:20260423T142327
CREATED:20230120T001538Z
LAST-MODIFIED:20230130T022602Z
UID:47835-1554440400-1554444000@csi.nus.edu.sg
SUMMARY:CSI Research Meeting - 5 April
DESCRIPTION:The CSI State-of-the-Institute address 2019 will commence at 1pm.Regular CSI Research Meeting talks as below will start after the State-of-the-Institute address\, followed by refreshments at 2.30pm.\nAll staff and students are encouraged to attend.
URL:https://csi.nus.edu.sg/event/csi-research-meeting-5-april/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190408T030000
DTEND;TZID=UTC:20190408T040000
DTSTAMP:20260423T142327
CREATED:20230120T001735Z
LAST-MODIFIED:20230130T022522Z
UID:47866-1554692400-1554696000@csi.nus.edu.sg
SUMMARY:RNA Club - 8 Apr
DESCRIPTION:Speaker: Dr Jordan SkittrallVenue: NUS\, MD6\, Level 12 conference room\nTime: 11 am\nTitle:  In silico prediction of RNA secondary structure and function using big data approaches to primary structures|\nHost: Prof. Andrew Lever \n 
URL:https://csi.nus.edu.sg/event/rna-club-8-apr/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190416T050000
DTEND;TZID=UTC:20190416T090000
DTSTAMP:20260423T142327
CREATED:20230120T001608Z
LAST-MODIFIED:20230130T022426Z
UID:47845-1555390800-1555405200@csi.nus.edu.sg
SUMMARY:Bioinformatics Workshop - 16 Apr
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/bioinformatics-workshop-16-apr/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190416T070700
DTEND;TZID=UTC:20190416T070700
DTSTAMP:20260423T142328
CREATED:20230119T222955Z
LAST-MODIFIED:20230119T222955Z
UID:47373-1555398420-1555398420@csi.nus.edu.sg
SUMMARY:CSI-Advances in Research (AIR) Meeting
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/csi-advances-in-research-air-meeting/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190416T070700
DTEND;TZID=UTC:20190416T070700
DTSTAMP:20260423T142328
CREATED:20230119T222956Z
LAST-MODIFIED:20230119T222956Z
UID:47374-1555398420-1555398420@csi.nus.edu.sg
SUMMARY:16th Asia-Pacific International Molecular Biology Network Conference
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/16th-asia-pacific-international-molecular-biology-network-conference/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190416T070700
DTEND;TZID=UTC:20190416T070700
DTSTAMP:20260423T142328
CREATED:20230119T222957Z
LAST-MODIFIED:20230119T222957Z
UID:47375-1555398420-1555398420@csi.nus.edu.sg
SUMMARY:Joint SGCC-CSI Gastric Cancer Seminar
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/joint-sgcc-csi-gastric-cancer-seminar/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190416T070700
DTEND;TZID=UTC:20190416T070700
DTSTAMP:20260423T142328
CREATED:20230119T222958Z
LAST-MODIFIED:20230119T222958Z
UID:47376-1555398420-1555398420@csi.nus.edu.sg
SUMMARY:CSI-Advances in Research – YONG Kol Jia
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/csi-advances-in-research-yong-kol-jia/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190416T070700
DTEND;TZID=UTC:20190416T070700
DTSTAMP:20260423T142328
CREATED:20230119T222958Z
LAST-MODIFIED:20230119T222958Z
UID:47377-1555398420-1555398420@csi.nus.edu.sg
SUMMARY:CSI RESEARCH MEETING
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/csi-research-meeting/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190416T070700
DTEND;TZID=UTC:20190416T070700
DTSTAMP:20260423T142328
CREATED:20230119T222959Z
LAST-MODIFIED:20230130T022316Z
UID:47378-1555398420-1555398420@csi.nus.edu.sg
SUMMARY:Frontiers in Cancer Science 2015
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/frontiers-in-cancer-science-2015/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190416T070700
DTEND;TZID=UTC:20190416T070700
DTSTAMP:20260423T142328
CREATED:20230119T223014Z
LAST-MODIFIED:20230119T223014Z
UID:47383-1555398420-1555398420@csi.nus.edu.sg
SUMMARY:NUS Scientists Develop Novel Chemical "Dye" to Improve Liver Cancer Imaging
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/nus-scientists-develop-novel-chemical-dye-to-improve-liver-cancer-imaging/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190416T070700
DTEND;TZID=UTC:20190416T070700
DTSTAMP:20260423T142328
CREATED:20230119T223014Z
LAST-MODIFIED:20230119T223014Z
UID:47382-1555398420-1555398420@csi.nus.edu.sg
SUMMARY:CSI Research Meeting - 16 Jun
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/csi-research-meeting-16-jun/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190416T070700
DTEND;TZID=UTC:20190416T070700
DTSTAMP:20260423T142328
CREATED:20230119T223015Z
LAST-MODIFIED:20230119T223015Z
UID:47384-1555398420-1555398420@csi.nus.edu.sg
SUMMARY:NUS-CMU Joint Symposium
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/nus-cmu-joint-symposium/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190416T070700
DTEND;TZID=UTC:20190416T070700
DTSTAMP:20260423T142328
CREATED:20230119T223028Z
LAST-MODIFIED:20230119T223028Z
UID:47385-1555398420-1555398420@csi.nus.edu.sg
SUMMARY:CSI Seminar - Li Chai
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/csi-seminar-li-chai/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190416T070700
DTEND;TZID=UTC:20190416T070700
DTSTAMP:20260423T142328
CREATED:20230119T223028Z
LAST-MODIFIED:20230119T223028Z
UID:47386-1555398420-1555398420@csi.nus.edu.sg
SUMMARY:RNA Club – 9 OCT
DESCRIPTION:
URL:https://csi.nus.edu.sg/event/rna-club-9-oct/
END:VEVENT
END:VCALENDAR